Adenovirus-mediated transfer of a modified human proinsulin gene reverses hyperglycemia in diabetic mice. [electronic resource]
Producer: 19981214Description: E748-56 p. digitalISSN:- 0002-9513
- Adenoviridae
- Amino Acid Sequence
- Animals
- Blood Glucose -- metabolism
- CHO Cells
- Cell Line
- Chromatography, Gel
- Cricetinae
- Diabetes Mellitus, Experimental -- blood
- Gene Transfer Techniques
- Humans
- Hyperglycemia -- therapy
- Insulin -- biosynthesis
- Insulin Secretion
- Kidney
- Liver -- metabolism
- Liver Glycogen -- metabolism
- Liver Neoplasms, Experimental
- Mice
- Mice, Inbred C57BL
- Proinsulin -- biosynthesis
- Protein Processing, Post-Translational
- Receptor, Insulin -- metabolism
- Recombinant Fusion Proteins -- biosynthesis
- Transfection -- methods
- beta-Galactosidase -- biosynthesis
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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