Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements. [electronic resource]
Producer: 20160328Description: 1143-9 p. digitalISSN:- 1548-7105
- CRISPR-Associated Proteins -- genetics
- CRISPR-Cas Systems -- genetics
- Clustered Regularly Interspaced Short Palindromic Repeats -- genetics
- Enhancer Elements, Genetic
- Epigenesis, Genetic
- Epigenomics -- methods
- Gene Expression Regulation, Viral
- Globins -- genetics
- HEK293 Cells
- Humans
- K562 Cells
- Lentivirus -- genetics
- RNA, Guide, CRISPR-Cas Systems -- genetics
- Regulatory Elements, Transcriptional -- genetics
- Repressor Proteins -- genetics
- Viral Proteins -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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