Deficiency of the 15-kDa selenoprotein led to cytoskeleton remodeling and non-apoptotic membrane blebbing through a RhoA/ROCK pathway. [electronic resource]
Producer: 20150422Description: 884-90 p. digitalISSN:- 1090-2104
- Amides -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Membrane Structures -- drug effects
- Cytoskeleton -- drug effects
- Gene Knockdown Techniques
- Humans
- Myosin-Light-Chain Kinase -- antagonists & inhibitors
- Pyridines -- pharmacology
- Selenoproteins -- deficiency
- Signal Transduction -- drug effects
- rho-Associated Kinases -- metabolism
- rhoA GTP-Binding Protein -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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