Vandetanib sensitizes head and neck squamous cell carcinoma to photodynamic therapy through modulation of EGFR-dependent DNA repair and the tumour microenvironment. [electronic resource]
Producer: 20200210Description: 367-374 p. digitalISSN:- 1873-1597
- Animals
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival
- Chlorophyllides
- DNA Damage -- drug effects
- DNA-Activated Protein Kinase -- metabolism
- Down-Regulation
- Drug Therapy, Combination
- ErbB Receptors -- antagonists & inhibitors
- Head and Neck Neoplasms -- drug therapy
- Humans
- Mice
- Mice, Nude
- Photochemotherapy -- methods
- Photosensitizing Agents -- pharmacology
- Piperidines -- pharmacology
- Porphyrins -- pharmacology
- Quinazolines -- pharmacology
- Squamous Cell Carcinoma of Head and Neck -- drug therapy
- Tumor Microenvironment -- drug effects
- Vascular Endothelial Growth Factor Receptor-2 -- antagonists & inhibitors
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Publication Type: Journal Article
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