Results
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1.
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High-throughput high-content imaging assays for identification and characterization of selective AXL pathway inhibitors. [electronic resource] by
- Tang, Huaping
- Yang, Jing
- Shen, Ding Ren
- Calambur, Deepa
- Witmer, Mark
- Wu, Sophie
- Carpenter, Brian
- Zhang, Yaqun
- Gao, Mian
- Constantine, Keith
- Zhang, Litao
- Cvijic, Mary Ellen
Producer: 20141009
In:
Assay and drug development technologies vol. 12
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2.
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Discovery of 2-amino-heteroaryl-benzothiazole-6-anilides as potent p56(lck) inhibitors. [electronic resource] by
- Das, Jagabandhu
- Moquin, Robert V
- Lin, James
- Liu, Chunjian
- Doweyko, Arthur M
- DeFex, Henry F
- Fang, Qiong
- Pang, Suhong
- Pitt, Sidney
- Shen, Ding Ren
- Schieven, Gary L
- Barrish, Joel C
- Wityak, John
Producer: 20040315
In:
Bioorganic & medicinal chemistry letters vol. 13
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3.
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Integrating High-Content Analysis into a Multiplexed Screening Approach to Identify and Characterize GPCR Agonists. [electronic resource] by
- Zhu, Yingjie
- Watson, John
- Chen, Mengjie
- Shen, Ding Ren
- Yarde, Melissa
- Agler, Michele
- Burford, Neil
- Alt, Andrew
- Jayachandra, Sukhanya
- Cvijic, Mary Ellen
- Zhang, Litao
- Dyckman, Alaric
- Xie, Jenny
- O'Connell, Jonathan
- Banks, Martyn
- Weston, Andrea
Producer: 20161213
In:
Journal of biomolecular screening vol. 19
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4.
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Development of novel, 384-well high-throughput assay panels for human drug transporters: drug interaction and safety assessment in support of discovery research. [electronic resource] by
- Tang, Huaping
- Shen, Ding Ren
- Han, Yong-Hae
- Kong, Yan
- Balimane, Praveen
- Marino, Anthony
- Gao, Mian
- Wu, Sophie
- Xie, Dianlin
- Soars, Matthew G
- O'Connell, Jonathan C
- Rodrigues, A David
- Zhang, Litao
- Cvijic, Mary Ellen
Producer: 20140408
In:
Journal of biomolecular screening vol. 18
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5.
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Molecular design, synthesis, and structure-Activity relationships leading to the potent and selective p56(lck) inhibitor BMS-243117. [electronic resource] by
- Das, Jagabandhu
- Lin, James
- Moquin, Robert V
- Shen, Zhongqi
- Spergel, Steven H
- Wityak, John
- Doweyko, Arthur M
- DeFex, Henry F
- Fang, Qiong
- Pang, Suhong
- Pitt, Sidney
- Shen, Ding Ren
- Schieven, Gary L
- Barrish, Joel C
Producer: 20040301
In:
Bioorganic & medicinal chemistry letters vol. 13
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6.
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Discovery and initial SAR of 2-amino-5-carboxamidothiazoles as inhibitors of the Src-family kinase p56(Lck). [electronic resource] by
- Wityak, John
- Das, Jagabandhu
- Moquin, Robert V
- Shen, Zhongqi
- Lin, James
- Chen, Ping
- Doweyko, Arthur M
- Pitt, Sidney
- Pang, Suhong
- Shen, Ding Ren
- Fang, Qiong
- de Fex, Henry F
- Schieven, Gary L
- Kanner, Steven B
- Barrish, Joel C
Producer: 20040706
In:
Bioorganic & medicinal chemistry letters vol. 13
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7.
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Synthesis and SAR of novel imidazoquinoxaline-based Lck inhibitors: improvement of cell potency. [electronic resource] by
- Chen, Ping
- Iwanowicz, Edwin J
- Norris, Derek
- Gu, Henry H
- Lin, James
- Moquin, Robert V
- Das, Jagabandhu
- Wityak, John
- Spergel, Steven H
- de Fex, Henry
- Pang, Suhong
- Pitt, Sydney
- Shen, Ding Ren
- Schieven, Gary L
- Barrish, Joel C
Producer: 20030318
In:
Bioorganic & medicinal chemistry letters vol. 12
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8.
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Pyrazolo-pyrimidines: a novel heterocyclic scaffold for potent and selective p38 alpha inhibitors. [electronic resource] by
- Das, Jagabandhu
- Moquin, Robert V
- Pitt, Sidney
- Zhang, Rosemary
- Shen, Ding Ren
- McIntyre, Kim W
- Gillooly, Kathleen
- Doweyko, Arthur M
- Sack, John S
- Zhang, Hongjian
- Kiefer, Susan E
- Kish, Kevin
- McKinnon, Murray
- Barrish, Joel C
- Dodd, John H
- Schieven, Gary L
- Leftheris, Katerina
Producer: 20080516
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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9.
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Discovery of novel 2-(aminoheteroaryl)-thiazole-5-carboxamides as potent and orally active Src-family kinase p56(Lck) inhibitors. [electronic resource] by
- Chen, Ping
- Norris, Derek
- Das, Jagabandhu
- Spergel, Steven H
- Wityak, John
- Leith, Leslie
- Zhao, Rulin
- Chen, Bang-Chi
- Pitt, Sidney
- Pang, Suhong
- Shen, Ding Ren
- Zhang, Rosemary
- De Fex, Henry F
- Doweyko, Arthur M
- McIntyre, Kim W
- Shuster, David J
- Behnia, Kamelia
- Schieven, Gary L
- Barrish, Joel C
Producer: 20050420
In:
Bioorganic & medicinal chemistry letters vol. 14
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10.
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5-Cyanopyrimidine derivatives as a novel class of potent, selective, and orally active inhibitors of p38alpha MAP kinase. [electronic resource] by
- Liu, Chunjian
- Wrobleski, Stephen T
- Lin, James
- Ahmed, Gulzar
- Metzger, Axel
- Wityak, John
- Gillooly, Kathleen M
- Shuster, David J
- McIntyre, Kim W
- Pitt, Sidney
- Shen, Ding Ren
- Zhang, Rosemary F
- Zhang, Hongjian
- Doweyko, Arthur M
- Diller, David
- Henderson, Ian
- Barrish, Joel C
- Dodd, John H
- Schieven, Gary L
- Leftheris, Katerina
Producer: 20051128
In:
Journal of medicinal chemistry vol. 48
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11.
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5-amino-pyrazoles as potent and selective p38α inhibitors. [electronic resource] by
- Das, Jagabandhu
- Moquin, Robert V
- Dyckman, Alaric J
- Li, Tianle
- Pitt, Sidney
- Zhang, Rosemary
- Shen, Ding Ren
- McIntyre, Kim W
- Gillooly, Kathleen
- Doweyko, Arthur M
- Newitt, John A
- Sack, John S
- Zhang, Hongjian
- Kiefer, Susan E
- Kish, Kevin
- McKinnon, Murray
- Barrish, Joel C
- Dodd, John H
- Schieven, Gary L
- Leftheris, Katerina
Producer: 20110223
In:
Bioorganic & medicinal chemistry letters vol. 20
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12.
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Discovery of pyrrolo[2,1-f][1,2,4]triazine C6-ketones as potent, orally active p38α MAP kinase inhibitors. [electronic resource] by
- Dyckman, Alaric J
- Li, Tianle
- Pitt, Sidney
- Zhang, Rosemary
- Shen, Ding Ren
- McIntyre, Kim W
- Gillooly, Kathleen M
- Shuster, David J
- Doweyko, Arthur M
- Sack, John S
- Kish, Kevin
- Kiefer, Susan E
- Newitt, John A
- Zhang, Hongjian
- Marathe, Punit H
- McKinnon, Murray
- Barrish, Joel C
- Dodd, John H
- Schieven, Gary L
- Leftheris, Katerina
Producer: 20111122
In:
Bioorganic & medicinal chemistry letters vol. 21
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13.
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2-aminothiazole as a novel kinase inhibitor template. Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (dasatinib, BMS-354825) as a potent pan-Src kinase inhibitor. [electronic resource] by
- Das, Jagabandhu
- Chen, Ping
- Norris, Derek
- Padmanabha, Ramesh
- Lin, James
- Moquin, Robert V
- Shen, Zhongqi
- Cook, Lynda S
- Doweyko, Arthur M
- Pitt, Sidney
- Pang, Suhong
- Shen, Ding Ren
- Fang, Qiong
- de Fex, Henry F
- McIntyre, Kim W
- Shuster, David J
- Gillooly, Kathleen M
- Behnia, Kamelia
- Schieven, Gary L
- Wityak, John
- Barrish, Joel C
Producer: 20070119
In:
Journal of medicinal chemistry vol. 49
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14.
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Synthesis and SAR of new pyrrolo[2,1-f][1,2,4]triazines as potent p38 alpha MAP kinase inhibitors. [electronic resource] by
- Wrobleski, Stephen T
- Lin, Shuqun
- Hynes, John
- Wu, Hong
- Pitt, Sidney
- Shen, Ding Ren
- Zhang, Rosemary
- Gillooly, Kathleen M
- Shuster, David J
- McIntyre, Kim W
- Doweyko, Arthur M
- Kish, Kevin F
- Tredup, Jeffrey A
- Duke, Gerald J
- Sack, John S
- McKinnon, Murray
- Dodd, John
- Barrish, Joel C
- Schieven, Gary L
- Leftheris, Katerina
Producer: 20080516
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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15.
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Discovery and initial SAR of imidazoquinoxalines as inhibitors of the Src-family kinase p56(Lck). [electronic resource] by
- Chen, Ping
- Norris, Derek
- Iwanowicz, Edwin J
- Spergel, Steven H
- Lin, James
- Gu, Henry H
- Shen, Zhongqi
- Wityak, John
- Lin, Tai-An
- Pang, Suhong
- De Fex, Henry F
- Pitt, Sidney
- Shen, Ding Ren
- Doweyko, Arthur M
- Bassolino, Donna A
- Roberge, Jacques Y
- Poss, Michael A
- Chen, Bang-Chi
- Schieven, Gary L
- Barrish, Joel C
Producer: 20020917
In:
Bioorganic & medicinal chemistry letters vol. 12
Availability: No items available.
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16.
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The discovery of (R)-2-(sec-butylamino)-N-(2-methyl-5-(methylcarbamoyl)phenyl) thiazole-5-carboxamide (BMS-640994)-A potent and efficacious p38alpha MAP kinase inhibitor. [electronic resource] by
- Hynes, John
- Wu, Hong
- Pitt, Sidney
- Shen, Ding Ren
- Zhang, Rosemary
- Schieven, Gary L
- Gillooly, Kathleen M
- Shuster, David J
- Taylor, Tracy L
- Yang, XiaoXia
- McIntyre, Kim W
- McKinnon, Murray
- Zhang, Hongjian
- Marathe, Punit H
- Doweyko, Arthur M
- Kish, Kevin
- Kiefer, Susan E
- Sack, John S
- Newitt, John A
- Barrish, Joel C
- Dodd, John
- Leftheris, Katerina
Producer: 20080609
In:
Bioorganic & medicinal chemistry letters vol. 18
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17.
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Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active RORγt Inverse Agonists. [electronic resource] by
- Duan, James J-W
- Lu, Zhonghui
- Jiang, Bin
- Stachura, Sylwia
- Weigelt, Carolyn A
- Sack, John S
- Khan, Javed
- Ruzanov, Max
- Galella, Michael A
- Wu, Dauh-Rurng
- Yarde, Melissa
- Shen, Ding-Ren
- Shuster, David J
- Borowski, Virna
- Xie, Jenny H
- Zhang, Lisa
- Vanteru, Sridhar
- Gupta, Arun Kumar
- Mathur, Arvind
- Zhao, Qihong
- Foster, William
- Salter-Cid, Luisa M
- Carter, Percy H
- Dhar, T G Murali
Publication details: ACS medicinal chemistry letters Mar 2019
In:
ACS medicinal chemistry letters vol. 10
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18.
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Imidazoquinoxaline Src-family kinase p56Lck inhibitors: SAR, QSAR, and the discovery of (S)-N-(2-chloro-6-methylphenyl)-2-(3-methyl-1-piperazinyl)imidazo- [1,5-a]pyrido[3,2-e]pyrazin-6-amine (BMS-279700) as a potent and orally active inhibitor with excellent in vivo antiinflammatory activity. [electronic resource] by
- Chen, Ping
- Doweyko, Arthur M
- Norris, Derek
- Gu, Henry H
- Spergel, Steven H
- Das, Jagabundhu
- Moquin, Robert V
- Lin, James
- Wityak, John
- Iwanowicz, Edwin J
- McIntyre, Kim W
- Shuster, David J
- Behnia, Kamelia
- Chong, Saeho
- de Fex, Henry
- Pang, Suhong
- Pitt, Sydney
- Shen, Ding Ren
- Thrall, Sara
- Stanley, Paul
- Kocy, Octavian R
- Witmer, Mark R
- Kanner, Steven B
- Schieven, Gary L
- Barrish, Joel C
Producer: 20040924
In:
Journal of medicinal chemistry vol. 47
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19.
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Design, synthesis, and anti-inflammatory properties of orally active 4-(phenylamino)-pyrrolo[2,1-f][1,2,4]triazine p38alpha mitogen-activated protein kinase inhibitors. [electronic resource] by
- Hynes, John
- Dyckman, Alaric J
- Lin, Shuqun
- Wrobleski, Stephen T
- Wu, Hong
- Gillooly, Kathleen M
- Kanner, Steven B
- Lonial, Herinder
- Loo, Derek
- McIntyre, Kim W
- Pitt, Sidney
- Shen, Ding Ren
- Shuster, David J
- Yang, Xiaoxia
- Zhang, Rosemary
- Behnia, Kamelia
- Zhang, Hongjian
- Marathe, Punit H
- Doweyko, Arthur M
- Tokarski, John S
- Sack, John S
- Pokross, Matthew
- Kiefer, Susan E
- Newitt, John A
- Barrish, Joel C
- Dodd, John
- Schieven, Gary L
- Leftheris, Katerina
Producer: 20080227
In:
Journal of medicinal chemistry vol. 51
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20.
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Discovery and Structure-Activity Relationship (SAR) of a Series of Ethanolamine-Based Direct-Acting Agonists of Sphingosine-1-phosphate (S1P1). [electronic resource] by
- Gilmore, John L
- Sheppeck, James E
- Watterson, Scott H
- Haque, Lauren
- Mukhopadhyay, Parag
- Tebben, Andrew J
- Galella, Michael A
- Shen, Ding Ren
- Yarde, Melissa
- Cvijic, Mary Ellen
- Borowski, Virna
- Gillooly, Kathleen
- Taylor, Tracy
- McIntyre, Kim W
- Warrack, Bethanne
- Levesque, Paul C
- Li, Julia P
- Cornelius, Georgia
- D'Arienzo, Celia
- Marino, Anthony
- Balimane, Praveen
- Salter-Cid, Luisa
- Barrish, Joel C
- Pitts, William J
- Carter, Percy H
- Xie, Jenny
- Dyckman, Alaric J
Producer: 20170529
In:
Journal of medicinal chemistry vol. 59
Availability: No items available.
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