Results
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Synthesis, stereochemical determination and biochemical characterization of the enantiomeric phosphate esters of the novel immunosuppressive agent FTY720. [electronic resource] by
- Hale, Jeffrey J
- Yan, Lin
- Neway, William E
- Hajdu, Richard
- Bergstrom, James D
- Milligan, James A
- Shei, Gan-Ju
- Chrebet, Gary L
- Thornton, Rosemary A
- Card, Deborah
- Rosenbach, Mark
- Mandala, Suzanne
Producer: 20050307
In:
Bioorganic & medicinal chemistry vol. 12
Availability: No items available.
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4.
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SAR studies of 3-arylpropionic acids as potent and selective agonists of sphingosine-1-phosphate receptor-1 (S1P1) with enhanced pharmacokinetic properties. [electronic resource] by
- Yan, Lin
- Huo, Pei
- Hale, Jeffrey J
- Mills, Sander G
- Hajdu, Richard
- Keohane, Carol A
- Rosenbach, Mark J
- Milligan, James A
- Shei, Gan-Ju
- Chrebet, Gary
- Bergstrom, James
- Card, Deborah
- Mandala, Suzanne M
Producer: 20070403
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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5.
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The discovery of 3-(N-alkyl)aminopropylphosphonic acids as potent S1P receptor agonists. [electronic resource] by
- Hale, Jeffrey J
- Doherty, George
- Toth, Leslie
- Li, Zhen
- Mills, Sander G
- Hajdu, Richard
- Ann Keohane, Carol
- Rosenbach, Mark
- Milligan, James
- Shei, Gan-Ju
- Chrebet, Gary
- Bergstrom, James
- Card, Deborah
- Rosen, Hugh
- Mandala, Suzanne
Producer: 20050202
In:
Bioorganic & medicinal chemistry letters vol. 14
Availability: No items available.
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6.
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Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists. [electronic resource] by
- Mandala, Suzanne
- Hajdu, Richard
- Bergstrom, James
- Quackenbush, Elizabeth
- Xie, Jenny
- Milligan, James
- Thornton, Rosemary
- Shei, Gan-Ju
- Card, Deborah
- Keohane, CarolAnn
- Rosenbach, Mark
- Hale, Jeffrey
- Lynch, Christopher L
- Rupprecht, Kathleen
- Parsons, William
- Rosen, Hugh
Producer: 20020506
In:
Science (New York, N.Y.) vol. 296
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7.
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2-Aryl(pyrrolidin-4-yl)acetic acids are potent agonists of sphingosine-1-phosphate (S1P) receptors. [electronic resource] by
- Yan, Lin
- Budhu, Richard
- Huo, Pei
- Lynch, Christopher L
- Hale, Jeffrey J
- Mills, Sander G
- Hajdu, Richard
- Keohane, Carol A
- Rosenbach, Mark J
- Milligan, James A
- Shei, Gan-Ju
- Chrebet, Gary
- Bergstrom, James
- Card, Deborah
- Mandala, Suzanne M
Producer: 20060802
In:
Bioorganic & medicinal chemistry letters vol. 16
Availability: No items available.
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8.
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2,5-Disubstituted pyrrolidine carboxylates as potent, orally active sphingosine-1-phosphate (S1P) receptor agonists. [electronic resource] by
- Colandrea, Vincent J
- Legiec, Irene E
- Huo, Pei
- Yan, Lin
- Hale, Jeffrey J
- Mills, Sander G
- Bergstrom, James
- Card, Deborah
- Chebret, Gary
- Hajdu, Richard
- Keohane, Carol Ann
- Milligan, James A
- Rosenbach, Mark J
- Shei, Gan-Ju
- Mandala, Suzanne M
Producer: 20060802
In:
Bioorganic & medicinal chemistry letters vol. 16
Availability: No items available.
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9.
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Potent S1P receptor agonists replicate the pharmacologic actions of the novel immune modulator FTY720. [electronic resource] by
- Hale, Jeffrey J
- Neway, William
- Mills, Sander G
- Hajdu, Richard
- Ann Keohane, Carol
- Rosenbach, Mark
- Milligan, James
- Shei, Gan-Ju
- Chrebet, Gary
- Bergstrom, James
- Card, Deborah
- Koo, Gloria C
- Koprak, Sam L
- Jackson, Jesse J
- Rosen, Hugh
- Mandala, Suzanne
Producer: 20050106
In:
Bioorganic & medicinal chemistry letters vol. 14
Availability: No items available.
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10.
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Discovery of 3-arylpropionic acids as potent agonists of sphingosine-1-phosphate receptor-1 (S1P1) with high selectivity against all other known S1P receptor subtypes. [electronic resource] by
- Yan, Lin
- Huo, Pei
- Doherty, George
- Toth, Lesile
- Hale, Jeffrey J
- Mills, Sander G
- Hajdu, Richard
- Keohane, Carol A
- Rosenbach, Mark J
- Milligan, James A
- Shei, Gan-Ju
- Chrebet, Gary
- Bergstrom, James
- Card, Deborah
- Quackenbush, Elizabeth
- Wickham, Alexandra
- Mandala, Suzanne M
Producer: 20060925
In:
Bioorganic & medicinal chemistry letters vol. 16
Availability: No items available.
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11.
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Design and synthesis of conformationally constrained 3-(N-alkylamino)propylphosphonic acids as potent agonists of sphingosine-1-phosphate (S1P) receptors. [electronic resource] by
- Yan, Lin
- Hale, Jeffrey J
- Lynch, Christopher L
- Budhu, Richard
- Gentry, Amy
- Mills, Sander G
- Hajdu, Richard
- Keohane, Carol Ann
- Rosenbach, Mark J
- Milligan, James A
- Shei, Gan-Ju
- Chrebet, Gary
- Bergstrom, James
- Card, Deborah
- Rosen, Hugh
- Mandala, Suzanne M
Producer: 20050324
In:
Bioorganic & medicinal chemistry letters vol. 14
Availability: No items available.
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12.
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Selecting against S1P3 enhances the acute cardiovascular tolerability of 3-(N-benzyl)aminopropylphosphonic acid S1P receptor agonists. [electronic resource] by
- Hale, Jeffrey J
- Doherty, George
- Toth, Leslie
- Mills, Sander G
- Hajdu, Richard
- Keohane, Carol Ann
- Rosenbach, Mark
- Milligan, James
- Shei, Gan-Ju
- Chrebet, Gary
- Bergstrom, James
- Card, Deborah
- Forrest, Michael
- Sun, Shu-Yu
- West, Sarah
- Xie, Huijuan
- Nomura, Naomi
- Rosen, Hugh
- Mandala, Suzanne
Producer: 20050202
In:
Bioorganic & medicinal chemistry letters vol. 14
Availability: No items available.
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13.
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A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists. [electronic resource] by
- Hale, Jeffrey J
- Lynch, Christopher L
- Neway, William
- Mills, Sander G
- Hajdu, Richard
- Keohane, Carol Ann
- Rosenbach, Mark J
- Milligan, James A
- Shei, Gan-Ju
- Parent, Stephen A
- Chrebet, Gary
- Bergstrom, James
- Card, Deborah
- Ferrer, Marc
- Hodder, Peter
- Strulovici, Berta
- Rosen, Hugh
- Mandala, Suzanne
Producer: 20050214
In:
Journal of medicinal chemistry vol. 47
Availability: No items available.
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14.
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Discovery of potent 3,5-diphenyl-1,2,4-oxadiazole sphingosine-1-phosphate-1 (S1P1) receptor agonists with exceptional selectivity against S1P2 and S1P3. [electronic resource] by
- Li, Zhen
- Chen, Weirong
- Hale, Jeffrey J
- Lynch, Christopher L
- Mills, Sander G
- Hajdu, Richard
- Keohane, Carol Ann
- Rosenbach, Mark J
- Milligan, James A
- Shei, Gan-Ju
- Chrebet, Gary
- Parent, Stephen A
- Bergstrom, James
- Card, Deborah
- Forrest, Michael
- Quackenbush, Elizabeth J
- Wickham, L Alexandra
- Vargas, Hugo
- Evans, Rose M
- Rosen, Hugh
- Mandala, Suzanne
Producer: 20051128
In:
Journal of medicinal chemistry vol. 48
Availability: No items available.
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