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D-phenylglycinol-derived non-covalent factor Xa inhibitors: effect of non-peptidic S4 linkage elements on affinity and anticoagulant activity. [electronic resource] by
- Klimkowski, Valentine J
- Watson, Brian M
- Wiley, Michael R
- Liebeschuetz, John
- Franciskovich, Jeffry B
- Marimuthu, Jothirajah
- Bastian, Jolie A
- Sall, Daniel J
- Smallwood, Jeffrey K
- Chirgadze, Nikolay Y
- Smith, Gerald F
- Foster, Ronald S
- Craft, Trelia
- Sipes, Philip
- Chastain, Marcia
- Sheehan, Scott M
Producer: 20080205
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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A four component coupling strategy for the synthesis of D-phenylglycinamide-derived non-covalent factor Xa inhibitors. [electronic resource] by
- Sheehan, Scott M
- Masters, John J
- Wiley, Michael R
- Young, Stephen C
- Liebeschuetz, John W
- Jones, Stuart D
- Murray, Christopher W
- Franciskovich, Jeffrey B
- Engel, David B
- Weber, Wayne W
- Marimuthu, Jothirajah
- Kyle, Jeffrey A
- Smallwood, Jeffrey K
- Farmen, Mark W
- Smith, Gerald F
Producer: 20040227
In:
Bioorganic & medicinal chemistry letters vol. 13
Availability: No items available.
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6.
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Discovery of non-covalent dipeptidyl peptidase IV inhibitors which induce a conformational change in the active site. [electronic resource] by
- Sheehan, Scott M
- Mest, Hans-Juergen
- Watson, Brian M
- Klimkowski, Valentine J
- Timm, David E
- Cauvin, Annick
- Parsons, Stephen H
- Shi, Qing
- Canada, Emily J
- Wiley, Michael R
- Ruehter, Gerd
- Evers, Britta
- Petersen, Soenke
- Blaszczak, Larry C
- Pulley, Shon R
- Margolis, Brandon J
- Wishart, Graham N
- Renson, Beatrice
- Hankotius, Dirk
- Mohr, Michael
- Zechel, Johann-Christian
- Michael Kalbfleisch, J
- Dingess-Hammond, Elizabeth A
- Boelke, Andre
- Weichert, Andreas G
Producer: 20070529
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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7.
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Robust central reduction of amyloid-β in humans with an orally available, non-peptidic β-secretase inhibitor. [electronic resource] by
- May, Patrick C
- Dean, Robert A
- Lowe, Stephen L
- Martenyi, Ferenc
- Sheehan, Scott M
- Boggs, Leonard N
- Monk, Scott A
- Mathes, Brian M
- Mergott, Dustin J
- Watson, Brian M
- Stout, Stephanie L
- Timm, David E
- Smith Labell, Elizabeth
- Gonzales, Celedon R
- Nakano, Masako
- Jhee, Stanford S
- Yen, Mark
- Ereshefsky, Larry
- Lindstrom, Terry D
- Calligaro, David O
- Cocke, Patrick J
- Greg Hall, D
- Friedrich, Stuart
- Citron, Martin
- Audia, James E
Producer: 20120112
In:
The Journal of neuroscience : the official journal of the Society for Neuroscience vol. 31
Availability: No items available.
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8.
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The potent BACE1 inhibitor LY2886721 elicits robust central Aβ pharmacodynamic responses in mice, dogs, and humans. [electronic resource] by
- May, Patrick C
- Willis, Brian A
- Lowe, Stephen L
- Dean, Robert A
- Monk, Scott A
- Cocke, Patrick J
- Audia, James E
- Boggs, Leonard N
- Borders, Anthony R
- Brier, Richard A
- Calligaro, David O
- Day, Theresa A
- Ereshefsky, Larry
- Erickson, Jon A
- Gevorkyan, Hykop
- Gonzales, Celedon R
- James, Douglas E
- Jhee, Stanford S
- Komjathy, Steven F
- Li, Linglin
- Lindstrom, Terry D
- Mathes, Brian M
- Martényi, Ferenc
- Sheehan, Scott M
- Stout, Stephanie L
- Timm, David E
- Vaught, Grant M
- Watson, Brian M
- Winneroski, Leonard L
- Yang, Zhixiang
- Mergott, Dustin J
Producer: 20150324
In:
The Journal of neuroscience : the official journal of the Society for Neuroscience vol. 35
Availability: No items available.
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