The serine protease TMPRSS6 is required to sense iron deficiency. [electronic resource]
Producer: 20080602Description: 1088-92 p. digitalISSN:- 1095-9203
- Anemia, Macrocytic -- genetics
- Animals
- Antimicrobial Cationic Peptides -- genetics
- Cell Line, Tumor
- Gene Expression Regulation
- Hepcidins
- Humans
- Iron -- blood
- Iron Deficiencies
- Membrane Proteins -- chemistry
- Mice
- Mice, Mutant Strains
- Mice, Transgenic
- Models, Biological
- Mutation
- Phenotype
- Promoter Regions, Genetic
- Protein Structure, Tertiary
- Serine Endopeptidases -- chemistry
- Signal Transduction
- Transfection
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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