Sirt3 protects mitochondrial DNA damage and blocks the development of doxorubicin-induced cardiomyopathy in mice. [electronic resource]
Producer: 20160906Description: H962-72 p. digitalISSN:- 1522-1539
- 8-Hydroxy-2'-Deoxyguanosine
- Animals
- Cardiomegaly -- chemically induced
- Cardiomyopathies -- chemically induced
- Cell Death
- Cells, Cultured
- DNA Adducts -- metabolism
- DNA Damage
- DNA Glycosylases -- metabolism
- DNA, Mitochondrial -- genetics
- Deoxyguanosine -- analogs & derivatives
- Disease Models, Animal
- Doxorubicin
- Female
- Fibroblasts -- enzymology
- Hydrolysis
- Male
- Mice, Knockout
- Mitochondria, Heart -- enzymology
- Myocytes, Cardiac -- enzymology
- Oxidative Stress
- Rats, Sprague-Dawley
- Reactive Oxygen Species -- metabolism
- Sirtuin 3 -- deficiency
- Sirtuins -- metabolism
- Time Factors
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural
There are no comments on this title.
Log in to your account to post a comment.