Deficiency in Six2 during prenatal development is associated with reduced nephron number, chronic renal failure, and hypertension in Br/+ adult mice. [electronic resource]
Producer: 20090702Description: F1166-78 p. digitalISSN:- 1931-857X
- Animals
- Down-Regulation -- physiology
- Endothelin-1 -- metabolism
- Gene Expression Regulation, Developmental -- physiology
- Homeodomain Proteins -- genetics
- Hypertension, Renal -- genetics
- Kidney Failure, Chronic -- genetics
- Kidney Glomerulus -- abnormalities
- Kidney Tubules -- abnormalities
- Mice
- Mice, Inbred C3H
- Mice, Mutant Strains
- Microscopy, Electron
- Nephrons -- abnormalities
- Receptors, Endothelin -- metabolism
- Sodium-Potassium-Exchanging ATPase -- metabolism
- Transcription Factors -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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