Mutation of the caspase-3 cleavage site in the astroglial glutamate transporter EAAT2 delays disease progression and extends lifespan in the SOD1-G93A mouse model of ALS. [electronic resource]
Producer: 20170728Description: 145-153 p. digitalISSN:- 1090-2430
- Amyotrophic Lateral Sclerosis -- genetics
- Animals
- Astrocytes -- metabolism
- Caspase 3 -- metabolism
- Disease Models, Animal
- Disease Progression
- Excitatory Amino Acid Transporter 2 -- genetics
- Glutamic Acid -- genetics
- Intranuclear Inclusion Bodies -- metabolism
- Mice
- Motor Neurons -- metabolism
- Mutation -- genetics
- Superoxide Dismutase -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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