Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models. [electronic resource]
Producer: 20190617Description: 171-185.e25 p. digitalISSN:- 1097-4172
- Animals
- Apoptosis -- drug effects
- Casein Kinase Ialpha -- antagonists & inhibitors
- Cell Proliferation -- drug effects
- Cyclin-Dependent Kinase 9 -- antagonists & inhibitors
- Cyclin-Dependent Kinases -- antagonists & inhibitors
- DNA-Binding Proteins
- Disease Models, Animal
- Enhancer Elements, Genetic -- genetics
- Hematopoiesis
- Humans
- Leukemia, Myeloid, Acute -- drug therapy
- Mice
- Mice, Inbred C57BL
- Oncogene Proteins, Fusion -- metabolism
- Protein Serine-Threonine Kinases
- Proto-Oncogene Proteins
- Tumor Suppressor Protein p53 -- physiology
- Xenograft Model Antitumor Assays
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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