Identification of the first inhibitor of the GBP1:PIM1 interaction. Implications for the development of a new class of anticancer agents against paclitaxel resistant cancer cells. [electronic resource]
Producer: 20141218Description: 7916-32 p. digitalISSN:- 1520-4804
- Antineoplastic Agents -- chemical synthesis
- Binding Sites
- Cell Line, Tumor
- Computational Biology
- Drug Discovery
- Drug Resistance, Neoplasm
- GTP-Binding Proteins -- antagonists & inhibitors
- Humans
- Models, Molecular
- Molecular Docking Simulation
- Paclitaxel -- pharmacology
- Proto-Oncogene Proteins c-pim-1 -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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