The molecular tweezer CLR01 inhibits aberrant superoxide dismutase 1 (SOD1) self-assembly [electronic resource]
Producer: 20190520Description: 3501-3513 p. digitalISSN:- 1083-351X
- Amino Acid Sequence
- Amyotrophic Lateral Sclerosis -- genetics
- Animals
- Binding Sites
- Body Weight -- drug effects
- Bridged-Ring Compounds -- metabolism
- Disease Models, Animal
- Mice
- Muscle Strength -- drug effects
- Mutation
- Organophosphates -- metabolism
- Protein Aggregates -- drug effects
- Spinal Cord -- drug effects
- Superoxide Dismutase-1 -- chemistry
- Survival Analysis
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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