LPS/IFNgamma-induced RAW 264.7 apoptosis is regulated by both nitric oxide-dependent and -independent pathways involving JNK and the Bcl-2 family. [electronic resource]
Producer: 20080409Description: 1772-8 p. digitalISSN:- 1551-4005
- Animals
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- metabolism
- Bcl-2-Like Protein 11
- Cell Line
- Enzyme Activation -- drug effects
- Humans
- Interferon-gamma -- pharmacology
- JNK Mitogen-Activated Protein Kinases -- genetics
- Lipopolysaccharides -- pharmacology
- Macrophages -- cytology
- Membrane Proteins -- metabolism
- Mice
- Nitric Oxide -- metabolism
- Nitric Oxide Synthase Type II -- genetics
- Phosphorylation
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- RNA, Small Interfering -- genetics
- Signal Transduction -- physiology
- bcl-2-Associated X Protein -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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