Phosphorylation of a constrained azacyclic FTY720 analog enhances anti-leukemic activity without inducing S1P receptor activation. [electronic resource]
Producer: 20170901Description: 669-677 p. digitalISSN:- 1476-5551
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Disease Models, Animal
- Drug Resistance, Neoplasm -- genetics
- Female
- Fingolimod Hydrochloride -- pharmacology
- Humans
- Leukemia -- drug therapy
- Mice
- Phosphorylation
- Phosphotransferases (Alcohol Group Acceptor) -- genetics
- Receptors, Lysosphingolipid -- agonists
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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