A phase I study of a new polyamine biosynthesis inhibitor, SAM486A, in cancer patients with solid tumours. [electronic resource]
Producer: 20000915Description: 594-601 p. digitalISSN:- 0007-0920
- Adenosylmethionine Decarboxylase -- antagonists & inhibitors
- Adult
- Aged
- Agranulocytosis -- chemically induced
- Amidines -- adverse effects
- Antimetabolites, Antineoplastic -- therapeutic use
- Antineoplastic Agents -- adverse effects
- Area Under Curve
- Dose-Response Relationship, Drug
- Female
- Fluorodeoxyglucose F18
- Fluorouracil -- therapeutic use
- Humans
- Indans -- adverse effects
- Male
- Middle Aged
- Neoplasms -- drug therapy
- Polyamines -- chemistry
- Radiopharmaceuticals
- Time Factors
- Tomography, Emission-Computed
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Publication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article
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