Paramyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling. [electronic resource]
Producer: 20130220Description: 690-3 p. digitalISSN:- 1095-9203
- Adenosine Triphosphate -- metabolism
- Amino Acid Motifs
- Amino Acid Sequence
- Animals
- Crystallography, X-Ray
- DEAD Box Protein 58
- DEAD-box RNA Helicases -- chemistry
- HEK293 Cells
- Humans
- Hydrolysis
- Immunity, Innate
- Interferon-Induced Helicase, IFIH1
- Mice
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Parainfluenza Virus 5 -- immunology
- Protein Binding
- Protein Folding
- Protein Structure, Tertiary
- RNA, Double-Stranded -- metabolism
- Receptors, Immunologic
- Signal Transduction
- Sus scrofa
- Viral Proteins -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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