Makaluvamines vary in ability to induce dose-dependent DNA cleavage via topoisomerase II interaction. [electronic resource]
Producer: 19990601Description: 39-45 p. digitalISSN:- 0959-4973
- Animals
- Antineoplastic Agents -- pharmacology
- Carcinoma, Squamous Cell -- drug therapy
- DNA -- drug effects
- DNA Topoisomerases, Type II -- metabolism
- Dose-Response Relationship, Drug
- Enzyme Inhibitors -- metabolism
- Etoposide -- pharmacology
- Humans
- Mice
- Mice, Nude
- Nasopharyngeal Neoplasms -- drug therapy
- Pyrroles -- metabolism
- Quinolones -- metabolism
- Topoisomerase II Inhibitors
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Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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