Platelet factor 4/CXCL4 induces phagocytosis and the generation of reactive oxygen metabolites in mononuclear phagocytes independently of Gi protein activation or intracellular calcium transients. [electronic resource]
Producer: 20041102Description: 2060-7 p. digitalISSN:- 0022-1767
- Animals
- Calcium Signaling -- physiology
- Cell Differentiation -- drug effects
- Cells, Cultured -- drug effects
- Chemokine CCL5 -- pharmacology
- Drug Synergism
- GTP-Binding Protein alpha Subunits, Gi-Go -- physiology
- Humans
- Macrophage Activation -- drug effects
- Macrophages -- drug effects
- Mice
- Mice, Inbred C57BL
- Monocytes -- cytology
- N-Formylmethionine Leucyl-Phenylalanine -- pharmacology
- Phagocytosis -- drug effects
- Platelet Factor 4 -- pharmacology
- Reactive Oxygen Species -- metabolism
- Receptors, CXCR3
- Receptors, Chemokine -- physiology
- Respiratory Burst -- drug effects
- Species Specificity
- Stimulation, Chemical
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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