Novel ATP competitive MK2 inhibitors with potent biochemical and cell-based activity throughout the series. [electronic resource]
Producer: 20120803Description: 613-8 p. digitalISSN:- 1464-3405
- Benzamides -- pharmacology
- Chemistry, Pharmaceutical -- methods
- Computer Simulation
- Crystallography, X-Ray -- methods
- Cytokines -- metabolism
- Drug Design
- HSP27 Heat-Shock Proteins -- metabolism
- Heat-Shock Proteins
- Humans
- Intracellular Signaling Peptides and Proteins -- antagonists & inhibitors
- Models, Chemical
- Molecular Chaperones
- Phosphorylation
- Piperidones -- pharmacology
- Protein Kinase Inhibitors -- chemical synthesis
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Pyrroles -- chemistry
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article
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