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Structure-activity studies of diazabicyclo[3.3.0]octane-substituted pyrazines and pyridines as potent α4β2 nicotinic acetylcholine receptor ligands. [electronic resource] by
- Scanio, Marc J C
- Shi, Lei
- Bunnelle, William H
- Anderson, David J
- Helfrich, Rosalind J
- Malysz, John
- Thorin-Hagene, Kirsten K
- Van Handel, Ceclia E
- Marsh, Kennan C
- Lee, Chih-Hung
- Gopalakrishnan, Murali
Producer: 20120207
In:
Journal of medicinal chemistry vol. 54
Availability: No items available.
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7.
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Octahydropyrrolo[3,4-c]pyrrole: a diamine scaffold for construction of either alpha4beta2 or alpha7-selective nicotinic acetylcholine receptor (nAChR) ligands. Substitutions that switch subtype selectivity. [electronic resource] by
- Bunnelle, William H
- Tietje, Karin R
- Frost, Jennifer M
- Peters, Dan
- Ji, Jianguo
- Li, Tao
- Scanio, Marc J C
- Shi, Lei
- Anderson, David J
- Dyhring, Tino
- Grønlien, Jens H
- Ween, Hilde
- Thorin-Hagene, Kirsten
- Meyer, Michael D
Producer: 20090825
In:
Journal of medicinal chemistry vol. 52
Availability: No items available.
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8.
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Discovery of ABBV/GLPG-3221, a Potent Corrector of CFTR for the Treatment of Cystic Fibrosis. [electronic resource] by
- Scanio, Marc J C
- Searle, Xenia B
- Liu, Bo
- Koenig, John R
- Altenbach, Robert
- Gfesser, Gregory A
- Bogdan, Andrew
- Greszler, Stephen
- Zhao, Gang
- Singh, Ashvani
- Fan, Yihong
- Swensen, Andrew M
- Vortherms, Timothy
- Manelli, Arlene
- Balut, Corina
- Jia, Ying
- Gao, Wenqing
- Yong, Hong
- Schrimpf, Michael
- Tse, Chris
- Kym, Philip
- Wang, Xueqing
Publication details: ACS medicinal chemistry letters Nov 2019
In:
ACS medicinal chemistry letters vol. 10
Availability: No items available.
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9.
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Discovery and biological evaluation of potent, selective, orally bioavailable, pyrazine-based blockers of the Na(v)1.8 sodium channel with efficacy in a model of neuropathic pain. [electronic resource] by
- Scanio, Marc J C
- Shi, Lei
- Drizin, Irene
- Gregg, Robert J
- Atkinson, Robert N
- Thomas, James B
- Johnson, Matthew S
- Chapman, Mark L
- Liu, Dong
- Krambis, Michael J
- Liu, Yi
- Shieh, Char-Chang
- Zhang, Xufeng
- Simler, Gricelda H
- Joshi, Shailen
- Honore, Prisca
- Marsh, Kennan C
- Knox, Alison
- Werness, Stephen
- Antonio, Brett
- Krafte, Douglas S
- Jarvis, Michael F
- Faltynek, Connie R
- Marron, Brian E
- Kort, Michael E
Producer: 20110222
In:
Bioorganic & medicinal chemistry vol. 18
Availability: No items available.
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10.
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Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain. [electronic resource] by
- Drizin, Irene
- Gregg, Robert J
- Scanio, Marc J C
- Shi, Lei
- Gross, Michael F
- Atkinson, Robert N
- Thomas, James B
- Johnson, Matthew S
- Carroll, William A
- Marron, Brian E
- Chapman, Mark L
- Liu, Dong
- Krambis, Michael J
- Shieh, Char-Chang
- Zhang, XuFeng
- Hernandez, Gricelda
- Gauvin, Donna M
- Mikusa, Joseph P
- Zhu, Chang Z
- Joshi, Shailen
- Honore, Prisca
- Marsh, Kennan C
- Roeloffs, Rosemarie
- Werness, Stephen
- Krafte, Douglas S
- Jarvis, Michael F
- Faltynek, Connie R
- Kort, Michael E
Producer: 20080715
In:
Bioorganic & medicinal chemistry vol. 16
Availability: No items available.
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11.
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Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with efficacy in models of neuropathic and inflammatory pain. [electronic resource] by
- Kort, Michael E
- Drizin, Irene
- Gregg, Robert J
- Scanio, Marc J C
- Shi, Lei
- Gross, Michael F
- Atkinson, Robert N
- Johnson, Matthew S
- Pacofsky, Gregory J
- Thomas, James B
- Carroll, William A
- Krambis, Michael J
- Liu, Dong
- Shieh, Char-Chang
- Zhang, Xufeng
- Hernandez, Gricelda
- Mikusa, Joseph P
- Zhong, Chengmin
- Joshi, Shailen
- Honore, Prisca
- Roeloffs, Rosemarie
- Marsh, Kennan C
- Murray, Bernard P
- Liu, Jinrong
- Werness, Stephen
- Faltynek, Connie R
- Krafte, Douglas S
- Jarvis, Michael F
- Chapman, Mark L
- Marron, Brian E
Producer: 20080505
In:
Journal of medicinal chemistry vol. 51
Availability: No items available.
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12.
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Subtype-selective Na(v)1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives. [electronic resource] by
- Kort, Michael E
- Atkinson, Robert N
- Thomas, James B
- Drizin, Irene
- Johnson, Matthew S
- Secrest, Matthew A
- Gregg, Robert J
- Scanio, Marc J C
- Shi, Lei
- Hakeem, Ahmed H
- Matulenko, Mark A
- Chapman, Mark L
- Krambis, Michael J
- Liu, Dong
- Shieh, Char-Chang
- Zhang, XuFeng
- Simler, Gricelda
- Mikusa, Joseph P
- Zhong, Chengmin
- Joshi, Shailen
- Honore, Prisca
- Roeloffs, Rosemarie
- Werness, Stephen
- Antonio, Brett
- Marsh, Kennan C
- Faltynek, Connie R
- Krafte, Douglas S
- Jarvis, Michael F
- Marron, Brian E
Producer: 20110329
In:
Bioorganic & medicinal chemistry letters vol. 20
Availability: No items available.
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