RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks. [electronic resource]
Producer: 20170925Description: 374-386.e5 p. digitalISSN:- 1097-4164
- A549 Cells
- Animals
- BRCA2 Protein -- genetics
- CRISPR-Cas Systems
- DNA Breaks, Double-Stranded
- DNA Repair
- DNA, Neoplasm -- biosynthesis
- Dose-Response Relationship, Drug
- Drug Resistance, Neoplasm -- genetics
- Gene Expression Regulation, Neoplastic
- Genomic Instability
- HEK293 Cells
- Humans
- Mice
- Models, Molecular
- Mutation
- Neoplasms -- drug therapy
- Poly(ADP-ribose) Polymerase Inhibitors -- pharmacology
- Protein Binding
- RNA Interference
- Rad51 Recombinase -- genetics
- Replication Origin
- Transfection
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Publication Type: Journal Article
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