A collagen IV-derived peptide disrupts α5β1 integrin and potentiates Ang2/Tie2 signaling. [electronic resource]
Producer: 20200511ISSN:- 2379-3708
- Angiopoietin-2 -- genetics
- Animals
- Capillary Permeability -- drug effects
- Cell Line
- Collagen Type IV -- pharmacology
- Disease Models, Animal
- Endothelium, Vascular -- cytology
- Female
- Gene Knockdown Techniques
- Human Umbilical Vein Endothelial Cells
- Humans
- Inflammation -- drug therapy
- Integrin alpha5beta1 -- antagonists & inhibitors
- Lipopolysaccharides -- immunology
- Male
- Mice
- Mice, Transgenic
- Peptide Fragments -- pharmacology
- Peptides -- pharmacology
- Receptor, TIE-2 -- genetics
- Signal Transduction -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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