A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions. [electronic resource]
Producer: 20020606Description: 1948-56 p. digitalISSN:- 0261-4189
- Adherens Junctions
- Amino Acid Sequence
- Amyloid Precursor Protein Secretases
- Animals
- Aspartic Acid Endopeptidases
- Binding Sites
- Cadherins -- genetics
- Endopeptidases -- metabolism
- Humans
- Intracellular Fluid
- Matrix Metalloproteinases -- metabolism
- Membrane Proteins -- genetics
- Mice
- Mice, Knockout
- Molecular Sequence Data
- Presenilin-1
- Protein Processing, Post-Translational
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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