Comparative QSAR model generation using pyrazole derivatives for screening Janus kinase-1 inhibitors. [electronic resource]
Producer: 20210512Description: 503-519 p. digitalISSN:- 1747-0285
- Asthma -- drug therapy
- Binding Sites
- Humans
- Hydrophobic and Hydrophilic Interactions
- Inhibitory Concentration 50
- Interleukin-4 -- metabolism
- Janus Kinase 1 -- antagonists & inhibitors
- Janus Kinase 2 -- antagonists & inhibitors
- Molecular Docking Simulation
- Nitriles
- Protein Kinase Inhibitors -- chemistry
- Pyrazoles -- chemistry
- Pyrimidines
- Quantitative Structure-Activity Relationship
- STAT Transcription Factors
- Signal Transduction -- drug effects
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Publication Type: Journal Article
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