Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study. [electronic resource]
Producer: 20170914Description: e1002382 p. digitalISSN:- 1549-1676
- Adult
- Anemia, Sickle Cell -- drug therapy
- Azacitidine -- administration & dosage
- Decitabine
- Drug Therapy, Combination
- Enzyme Inhibitors -- administration & dosage
- Epigenesis, Genetic -- drug effects
- Female
- Fetal Hemoglobin -- drug effects
- Gene Expression Regulation -- drug effects
- Gene Silencing -- drug effects
- Humans
- Male
- Middle Aged
- Tetrahydrouridine -- administration & dosage
- Treatment Outcome
- Young Adult
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Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial
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