Identifying bias in CCR1 antagonists using radiolabelled binding, receptor internalization, β-arrestin translocation and chemotaxis assays. [electronic resource]
Producer: 20150702Description: 5127-38 p. digitalISSN:- 1476-5381
- Animals
- Arrestins -- metabolism
- CHO Cells
- Cell Line, Tumor
- Chemokine CCL3 -- metabolism
- Chemotaxis
- Cricetulus
- HEK293 Cells
- Humans
- Multiple Myeloma
- Phenylurea Compounds -- pharmacology
- Piperidines -- pharmacology
- Quinoxalines -- pharmacology
- Radioligand Assay
- Receptors, CCR1 -- antagonists & inhibitors
- Spiro Compounds -- pharmacology
- beta-Arrestins
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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