Isolation of a novel thioflavin S-derived compound that inhibits BAG-1-mediated protein interactions and targets BRAF inhibitor-resistant cell lines. [electronic resource]
Producer: 20140707Description: 2400-14 p. digitalISSN:- 1538-8514
- Aniline Compounds -- isolation & purification
- Animals
- Antineoplastic Agents -- isolation & purification
- Benzothiazoles -- isolation & purification
- Binding Sites -- drug effects
- Butadienes -- pharmacology
- Cell Line
- Cell Proliferation -- drug effects
- DNA-Binding Proteins -- antagonists & inhibitors
- Fluorescent Dyes -- metabolism
- HEK293 Cells
- HSC70 Heat-Shock Proteins -- metabolism
- Humans
- Indoles -- pharmacology
- MCF-7 Cells
- Mice
- Molecular Docking Simulation
- NIH 3T3 Cells
- Neoplasms -- drug therapy
- Nitriles -- pharmacology
- Protein Binding -- drug effects
- Proto-Oncogene Proteins B-raf -- antagonists & inhibitors
- Sulfonamides -- pharmacology
- Thiazoles -- chemistry
- Transcription Factors -- antagonists & inhibitors
- Vemurafenib
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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