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Structure-based design and parallel synthesis of N-benzyl isatin oximes as JNK3 MAP kinase inhibitors. [electronic resource] by
- Cao, Jingrong
- Gao, Huai
- Bemis, Guy
- Salituro, Francesco
- Ledeboer, Mark
- Harrington, Edmund
- Wilke, Susanne
- Taslimi, Paul
- Pazhanisamy, S
- Xie, Xiaoling
- Jacobs, Marc
- Green, Jeremy
Producer: 20090629
In:
Bioorganic & medicinal chemistry letters vol. 19
Availability: No items available.
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A novel chemotype of kinase inhibitors: Discovery of 3,4-ring fused 7-azaindoles and deazapurines as potent JAK2 inhibitors. [electronic resource] by
- Wang, Tiansheng
- Ledeboer, Mark W
- Duffy, John P
- Salituro, Francesco G
- Pierce, Albert C
- Zuccola, Harmon J
- Block, Eric
- Shlyakter, Dina
- Hogan, James K
- Bennani, Youssef L
Producer: 20100506
In:
Bioorganic & medicinal chemistry letters vol. 20
Availability: No items available.
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9.
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Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK). [electronic resource] by
- Farmer, Luc J
- Bemis, Guy
- Britt, Shawn D
- Cochran, John
- Connors, Martin
- Harrington, Edmund M
- Hoock, Thomas
- Markland, William
- Nanthakumar, Suganthini
- Taslimi, Paul
- Ter Haar, Ernst
- Wang, Jian
- Zhaveri, Darshana
- Salituro, Francesco G
Producer: 20090109
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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Neuroactive Steroids. 1. Positive Allosteric Modulators of the (γ-Aminobutyric Acid)A Receptor: Structure-Activity Relationships of Heterocyclic Substitution at C-21. [electronic resource] by
- Martinez Botella, Gabriel
- Salituro, Francesco G
- Harrison, Boyd L
- Beresis, Richard T
- Bai, Zhu
- Shen, Kaisheng
- Belfort, Gabriel M
- Loya, Carlos M
- Ackley, Michael A
- Grossman, Scott J
- Hoffmann, Ethan
- Jia, Shiling
- Wang, Jiamiao
- Doherty, James J
- Robichaud, Albert J
Producer: 20150629
In:
Journal of medicinal chemistry vol. 58
Availability: No items available.
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11.
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Neuroactive Steroid [electronic resource] by
- La, Daniel S
- Salituro, Francesco G
- Martinez Botella, Gabriel
- Griffin, Andrew M
- Bai, Zhu
- Ackley, Michael A
- Dai, Jing
- Doherty, James J
- Harrison, Boyd L
- Hoffmann, Ethan C
- Kazdoba, Tatiana M
- Lewis, Michael C
- Quirk, Michael C
- Robichaud, Albert J
Producer: 20200622
In:
Journal of medicinal chemistry vol. 62
Availability: No items available.
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12.
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Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1'-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric Acid) [electronic resource] by
- Martinez Botella, Gabriel
- Salituro, Francesco G
- Harrison, Boyd L
- Beresis, Richard T
- Bai, Zhu
- Blanco, Maria-Jesus
- Belfort, Gabriel M
- Dai, Jing
- Loya, Carlos M
- Ackley, Michael A
- Althaus, Alison L
- Grossman, Scott J
- Hoffmann, Ethan
- Doherty, James J
- Robichaud, Albert J
Producer: 20171016
In:
Journal of medicinal chemistry vol. 60
Availability: No items available.
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13.
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c-Jun N-terminal kinases mediate reactivation of Akt and cardiomyocyte survival after hypoxic injury in vitro and in vivo. [electronic resource] by
- Shao, Zhili
- Bhattacharya, Kausik
- Hsich, Eileen
- Park, Larry
- Walters, Brian
- Germann, Ursula
- Wang, Yow-Ming
- Kyriakis, John
- Mohanlal, Ramon
- Kuida, Keisuke
- Namchuk, Mark
- Salituro, Francesco
- Yao, Yung-mae
- Hou, Wei-min
- Chen, Xin
- Aronovitz, Mark
- Tsichlis, Philip N
- Bhattacharya, Susmita
- Force, Thomas
- Kilter, Heiko
Producer: 20060209
In:
Circulation research vol. 98
Availability: No items available.
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14.
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Discovery of the First Potent Inhibitors of Mutant IDH1 That Lower Tumor 2-HG in Vivo. [electronic resource] by
- Popovici-Muller, Janeta
- Saunders, Jeffrey O
- Salituro, Francesco G
- Travins, Jeremy M
- Yan, Shunqi
- Zhao, Fang
- Gross, Stefan
- Dang, Lenny
- Yen, Katharine E
- Yang, Hua
- Straley, Kimberly S
- Jin, Shengfang
- Kunii, Kaiko
- Fantin, Valeria R
- Zhang, Shunan
- Pan, Qiongqun
- Shi, Derek
- Biller, Scott A
- Su, Shinsan M
Producer: 20140605
In:
ACS medicinal chemistry letters vol. 3
Availability: No items available.
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15.
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2-Aminopyrazolo[1,5-a]pyrimidines as potent and selective inhibitors of JAK2. [electronic resource] by
- Ledeboer, Mark W
- Pierce, Albert C
- Duffy, John P
- Gao, Huai
- Messersmith, David
- Salituro, Francesco G
- Nanthakumar, Suganthini
- Come, Jon
- Zuccola, Harmon J
- Swenson, Lora
- Shlyakter, Dina
- Mahajan, Sudipta
- Hoock, Thomas
- Fan, Bin
- Tsai, Wan-Jung
- Kolaczkowski, Elaine
- Carrier, Scott
- Hogan, James K
- Zessis, Richard
- Pazhanisamy, S
- Bennani, Youssef L
Producer: 20100119
In:
Bioorganic & medicinal chemistry letters vol. 19
Availability: No items available.
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16.
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AG-348 enhances pyruvate kinase activity in red blood cells from patients with pyruvate kinase deficiency. [electronic resource] by
- Kung, Charles
- Hixon, Jeff
- Kosinski, Penelope A
- Cianchetta, Giovanni
- Histen, Gavin
- Chen, Yue
- Hill, Collin
- Gross, Stefan
- Si, Yaguang
- Johnson, Kendall
- DeLaBarre, Byron
- Luo, Zhiyong
- Gu, Zhiwei
- Yao, Gui
- Tang, Huachun
- Fang, Cheng
- Xu, Yingxia
- Lv, Xiaobing
- Biller, Scott
- Su, Shin-San Michael
- Yang, Hua
- Popovici-Muller, Janeta
- Salituro, Francesco
- Silverman, Lee
- Dang, Lenny
Producer: 20171002
In:
Blood vol. 130
Availability: No items available.
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17.
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Janus kinase 2 inhibitors. Synthesis and characterization of a novel polycyclic azaindole. [electronic resource] by
- Wang, Tiansheng
- Duffy, John P
- Wang, Jian
- Halas, Summer
- Salituro, Francesco G
- Pierce, Albert C
- Zuccola, Harmon J
- Black, James R
- Hogan, James K
- Jepson, Scott
- Shlyakter, Dina
- Mahajan, Sudipta
- Gu, Yong
- Hoock, Thomas
- Wood, Mark
- Furey, Brinley F
- Frantz, J Daniel
- Dauffenbach, Lisa M
- Germann, Ursula A
- Fan, Bin
- Namchuk, Mark
- Bennani, Youssef L
- Ledeboer, Mark W
Producer: 20100106
In:
Journal of medicinal chemistry vol. 52
Availability: No items available.
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18.
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The Discovery of VX-745: A Novel and Selective p38α Kinase Inhibitor. [electronic resource] by
- Duffy, John P
- Harrington, Edmund M
- Salituro, Francesco G
- Cochran, John E
- Green, Jeremy
- Gao, Huai
- Bemis, Guy W
- Evindar, Ghotas
- Galullo, Vincent P
- Ford, Pamella J
- Germann, Ursula A
- Wilson, Keith P
- Bellon, Steven F
- Chen, Guanging
- Taslimi, Paul
- Jones, Peter
- Huang, Cassey
- Pazhanisamy, S
- Wang, Yow-Ming
- Murcko, Mark A
- Su, Michael S S
Producer: 20140605
In:
ACS medicinal chemistry letters vol. 2
Availability: No items available.
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19.
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Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation. [electronic resource] by
- Wang, Fang
- Travins, Jeremy
- DeLaBarre, Byron
- Penard-Lacronique, Virginie
- Schalm, Stefanie
- Hansen, Erica
- Straley, Kimberly
- Kernytsky, Andrew
- Liu, Wei
- Gliser, Camelia
- Yang, Hua
- Gross, Stefan
- Artin, Erin
- Saada, Veronique
- Mylonas, Elena
- Quivoron, Cyril
- Popovici-Muller, Janeta
- Saunders, Jeffrey O
- Salituro, Francesco G
- Yan, Shunqi
- Murray, Stuart
- Wei, Wentao
- Gao, Yi
- Dang, Lenny
- Dorsch, Marion
- Agresta, Sam
- Schenkein, David P
- Biller, Scott A
- Su, Shinsan M
- de Botton, Stephane
- Yen, Katharine E
Producer: 20130521
In:
Science (New York, N.Y.) vol. 340
Availability: No items available.
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20.
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Small molecule activation of PKM2 in cancer cells induces serine auxotrophy. [electronic resource] by
- Kung, Charles
- Hixon, Jeff
- Choe, Sung
- Marks, Kevin
- Gross, Stefan
- Murphy, Erin
- DeLaBarre, Byron
- Cianchetta, Giovanni
- Sethumadhavan, Shalini
- Wang, Xiling
- Yan, Shunqi
- Gao, Yi
- Fang, Cheng
- Wei, Wentao
- Jiang, Fan
- Wang, Shaohui
- Qian, Kevin
- Saunders, Jeff
- Driggers, Ed
- Woo, Hin Koon
- Kunii, Kaiko
- Murray, Stuart
- Yang, Hua
- Yen, Katharine
- Liu, Wei
- Cantley, Lewis C
- Vander Heiden, Matthew G
- Su, Shinsan M
- Jin, Shengfang
- Salituro, Francesco G
- Dang, Lenny
Producer: 20140710
In:
Chemistry & biology vol. 19
Availability: No items available.
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