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5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part III: molecular modeling studies on binding contribution of 1-(5-methylsulfonyl)pyrid-2-yl and 4-nitrile. [electronic resource] by
- Sakya, Subas M
- Hou, Xinjun
- Minich, Martha L
- Rast, Bryson
- Shavnya, Andrei
- DeMello, Kristin M L
- Cheng, Hengmiao
- Li, Jin
- Jaynes, Burton H
- Mann, Donald W
- Petras, Carol F
- Seibel, Scott B
- Haven, Michelle L
Producer: 20070413
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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11.
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Comparative structure-activity relationship studies of 1-(5-methylsulfonylpyrid-2-yl)-5-alkyl and (hetero)aryl triazoles and pyrazoles in canine COX inhibition. [electronic resource] by
- Sakya, Subas M
- Shavnya, Andrei
- Cheng, Hengmiao
- Li, Chao
- Rast, Bryson
- Li, Jin
- Koss, David A
- Jaynes, Burton H
- Mann, Donald W
- Petras, Carol F
- Seibel, Scott B
- Haven, Michelle L
- Lynch, Michael P
Producer: 20080324
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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12.
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Azalide 3,6-ketals: antibacterial activity and structure-activity relationships of aryl and hetero aryl substituted analogues. [electronic resource] by
- Sakya, Subas M
- Bertinato, Peter
- Pratt, Bryan
- Suarez-Contreras, Melani
- Lundy, Kristin M
- Minich, Martha L
- Cheng, Hengmiao
- Ziegler, Carl B
- Kamicker, Barbara J
- Hayashi, Shigeru F
- Santoro, Sheryl L
- George, David M
- Bertsche, Camilla D
Producer: 20031103
In:
Bioorganic & medicinal chemistry letters vol. 13
Availability: No items available.
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13.
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Synthesis and SAR of azalide 3,6-ketal aromatic derivatives as potent Gram-positive and Gram-negative antibacterial agents. [electronic resource] by
- Cheng, Hengmiao
- Dirlam, John P
- Ziegler, Carl B
- Lundy, Kristin M
- Hayashi, Shigeru F
- Kamicker, Barbara J
- Dutra, Jason K
- Daniel, Kirsten L
- Santoro, Sheryl L
- George, David M
- Bertsche, Camilla D
- Sakya, Subas M
- Suarez-Contreras, Melani
Producer: 20030731
In:
Bioorganic & medicinal chemistry letters vol. 12
Availability: No items available.
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14.
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In vitro and in vivo profile of 2-(3-di-fluoromethyl-5-phenylpyrazol-1-yl)-5-methanesulfonylpyridine, a potent, selective, and orally active canine COX-2 inhibitor. [electronic resource] by
- Li, Jin
- Lynch, Michael P
- Demello, Kristin Lundy
- Sakya, Subas M
- Cheng, Hengmiao
- Rafka, Robert J
- Bronk, Brian S
- Jaynes, Burton H
- Kilroy, Carolyn
- Mann, Donald W
- Haven, Michelle L
- Kolosko, Nicole L
- Petras, Carol
- Seibel, Scott B
- Lund, Lisa A
Producer: 20050725
In:
Bioorganic & medicinal chemistry vol. 13
Availability: No items available.
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15.
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Design and synthesis of dihydrobenzofuran amides as orally bioavailable, centrally active γ-secretase modulators. [electronic resource] by
- Pettersson, Martin
- Johnson, Douglas S
- Subramanyam, Chakrapani
- Bales, Kelly R
- am Ende, Christopher W
- Fish, Benjamin A
- Green, Michael E
- Kauffman, Gregory W
- Lira, Ricardo
- Mullins, Patrick B
- Navaratnam, Thayalan
- Sakya, Subas M
- Stiff, Cory M
- Tran, Tuan P
- Vetelino, Beth C
- Xie, Longfei
- Zhang, Liming
- Pustilnik, Leslie R
- Wood, Kathleen M
- O'Donnell, Christopher J
Producer: 20120918
In:
Bioorganic & medicinal chemistry letters vol. 22
Availability: No items available.
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16.
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5-heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part 1: Structure-activity relationship studies of 5-alkylamino pyrazoles and discovery of a potent, selective, and orally active analog. [electronic resource] by
- Sakya, Subas M
- DeMello, Kristin M Lundy
- Minich, Martha L
- Rast, Bryson
- Shavnya, Andrei
- Rafka, Robert J
- Koss, David A
- Cheng, Hengmiao
- Li, Jin
- Jaynes, Burton H
- Ziegler, Carl B
- Mann, Donald W
- Petras, Carol F
- Seibel, Scott B
- Silvia, Annette M
- George, David M
- Lund, Lisa A
- St Denis, Suzanne
- Hickman, Anne
- Haven, Michelle L
- Lynch, Michael P
Producer: 20060302
In:
Bioorganic & medicinal chemistry letters vol. 16
Availability: No items available.
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17.
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Discovery, SAR, and pharmacokinetics of a novel 3-hydroxyquinolin-2(1H)-one series of potent D-amino acid oxidase (DAAO) inhibitors. [electronic resource] by
- Duplantier, Allen J
- Becker, Stacey L
- Bohanon, Michael J
- Borzilleri, Kris A
- Chrunyk, Boris A
- Downs, James T
- Hu, Lain-Yen
- El-Kattan, Ayman
- James, Larry C
- Liu, Shenping
- Lu, Jiemin
- Maklad, Noha
- Mansour, Mahmoud N
- Mente, Scot
- Piotrowski, Mary A
- Sakya, Subas M
- Sheehan, Susan
- Steyn, Stefanus J
- Strick, Christine A
- Williams, Victoria A
- Zhang, Lei
Producer: 20090701
In:
Journal of medicinal chemistry vol. 52
Availability: No items available.
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18.
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5-Heteroatom-substituted pyrazoles as canine COX-2 inhibitors: Part 2. Structure-activity relationship studies of 5-alkylethers and 5-thioethers. [electronic resource] by
- Sakya, Subas M
- Cheng, Hengmiao
- Lundy Demello, Kristin M
- Shavnya, Andrei
- Minich, Martha L
- Rast, Bryson
- Dutra, Jason
- Li, Chao
- Rafka, Robert J
- Koss, David A
- Li, Jin
- Jaynes, Burton H
- Ziegler, Carl B
- Mann, Donald W
- Petras, Carol F
- Seibel, Scott B
- Silvia, Annette M
- George, David M
- Hickman, Anne
- Haven, Michelle L
- Lynch, Michael P
Producer: 20060323
In:
Bioorganic & medicinal chemistry letters vol. 16
Availability: No items available.
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19.
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Design, synthesis, and pharmacological evaluation of a novel series of pyridopyrazine-1,6-dione γ-secretase modulators. [electronic resource] by
- Pettersson, Martin
- Johnson, Douglas S
- Subramanyam, Chakrapani
- Bales, Kelly R
- am Ende, Christopher W
- Fish, Benjamin A
- Green, Michael E
- Kauffman, Gregory W
- Mullins, Patrick B
- Navaratnam, Thayalan
- Sakya, Subas M
- Stiff, Cory M
- Tran, Tuan P
- Xie, Longfei
- Zhang, Liming
- Pustilnik, Leslie R
- Vetelino, Beth C
- Wood, Kathleen M
- Pozdnyakov, Nikolay
- Verhoest, Patrick R
- O'Donnell, Christopher J
Producer: 20140415
In:
Journal of medicinal chemistry vol. 57
Availability: No items available.
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20.
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Synthesis and SAR of heteroaryl-phenyl-substituted pyrazole derivatives as highly selective and potent canine COX-2 inhibitors. [electronic resource] by
- Cheng, Hengmiao
- Lundy DeMello, Kristin M
- Li, Jin
- Sakya, Subas M
- Ando, Kazuo
- Kawamura, K
- Kato, Tomoki
- Rafka, Robert J
- Jaynes, Burton H
- Ziegler, Carl B
- Stevens, Rod
- Lund, Lisa A
- Mann, Donald W
- Kilroy, Carolyn
- Haven, Michelle L
- Nimz, Erik L
- Dutra, Jason K
- Li, Chao
- Minich, Martha L
- Kolosko, Nicole L
- Petras, Carol
- Silvia, Annette M
- Seibel, Scott B
Producer: 20060607
In:
Bioorganic & medicinal chemistry letters vol. 16
Availability: No items available.
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