Design and development of ((4-methoxyphenyl)carbamoyl) (5-(5-nitrothiophen-2-yl)-1,3,4-thiadiazol-2-yl)amide analogues as Mycobacterium tuberculosis ketol-acid reductoisomerase inhibitors. [electronic resource]
Producer: 20201130Description: 112178 p. digitalISSN:- 1768-3254
- Amides -- chemical synthesis
- Animals
- Antitubercular Agents -- chemical synthesis
- Biofilms -- drug effects
- Cell Line
- Dose-Response Relationship, Drug
- Drug Development
- Enzyme Inhibitors -- chemical synthesis
- HEK293 Cells
- Humans
- Ketol-Acid Reductoisomerase -- antagonists & inhibitors
- Macrophages -- drug effects
- Mice
- Microbial Sensitivity Tests
- Models, Molecular
- Molecular Structure
- Mycobacterium tuberculosis -- drug effects
- Structure-Activity Relationship
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Publication Type: Journal Article
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