Induction of 8-hydroxydeoxyguanosine but not initiation of carcinogenesis by redox enzyme modulations with or without menadione in rat liver. [electronic resource]
Producer: 19910514Description: 719-26 p. digitalISSN:- 0143-3334
- 8-Hydroxy-2'-Deoxyguanosine
- Animals
- Body Weight -- drug effects
- Cytochrome Reductases -- biosynthesis
- DNA -- metabolism
- DNA Damage
- Deoxyguanosine -- analogs & derivatives
- Dicumarol -- pharmacology
- Glutathione -- metabolism
- Iron -- metabolism
- Ketones -- pharmacology
- Liver -- anatomy & histology
- Liver Neoplasms, Experimental -- enzymology
- Male
- NAD(P)H Dehydrogenase (Quinone)
- Necrosis
- Neoplasms, Experimental -- enzymology
- Organ Size -- drug effects
- Oxidation-Reduction
- Phenobarbital -- pharmacology
- Quinone Reductases -- antagonists & inhibitors
- Rats
- Rats, Inbred F344
- Time Factors
- Vitamin K -- pharmacology
- gamma-Glutamyltransferase -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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