Frequent attenuation of the WWOX tumor suppressor in osteosarcoma is associated with increased tumorigenicity and aberrant RUNX2 expression. [electronic resource]
Producer: 20100809Description: 5577-86 p. digitalISSN:- 1538-7445
- Animals
- Apoptosis -- physiology
- Bone Neoplasms -- drug therapy
- Cell Growth Processes -- physiology
- Cell Line, Tumor
- Cell Movement -- physiology
- Core Binding Factor Alpha 1 Subunit -- biosynthesis
- Disease Progression
- Female
- Humans
- Immunohistochemistry
- Mice
- Mice, Nude
- Osteosarcoma -- drug therapy
- Oxidoreductases -- biosynthesis
- Transcriptional Activation
- Tumor Suppressor Proteins -- biosynthesis
- WW Domain-Containing Oxidoreductase
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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