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Oxyguanidines: application to non-peptidic phenyl-based thrombin inhibitors. [electronic resource] by
- Tomczuk, Bruce
- Lu, Tianbao
- Soll, Richard M
- Fedde, Cynthia
- Wang, Aihua
- Murphy, Larry
- Crysler, Carl
- Dasgupta, Malini
- Eisennagel, Stephen
- Spurlino, John
- Bone, Roger
Producer: 20031205
In:
Bioorganic & medicinal chemistry letters vol. 13
Availability: No items available.
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7.
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Oxyguanidines. Part 2: Discovery of a novel orally active thrombin inhibitor through structure-based drug design and parallel synthesis. [electronic resource] by
- Lu, Tianbao
- Markotan, Thomas
- Coppo, Frank
- Tomczuk, Bruce
- Crysler, Carl
- Eisennagel, Stephen
- Spurlino, John
- Gremminger, Lisa
- Soll, Richard M
- Giardino, Edward C
- Bone, Roger
Producer: 20050207
In:
Bioorganic & medicinal chemistry letters vol. 14
Availability: No items available.
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8.
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Discovery of 3,3'-(2,4-diaminopteridine-6,7-diyl)diphenol as an isozyme-selective inhibitor of PI3K for the treatment of ischemia reperfusion injury associated with myocardial infarction. [electronic resource] by
- Palanki, Moorthy S S
- Dneprovskaia, Elena
- Doukas, John
- Fine, Richard M
- Hood, John
- Kang, Xinshan
- Lohse, Dan
- Martin, Michael
- Noronha, Glenn
- Soll, Richard M
- Wrasidlo, Wolfgang
- Yee, Shiyin
- Zhu, Hong
Producer: 20071101
In:
Journal of medicinal chemistry vol. 50
Availability: No items available.
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9.
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Selective inhibition of JAK2-driven erythroid differentiation of polycythemia vera progenitors. [electronic resource] by
- Geron, Ifat
- Abrahamsson, Annelie E
- Barroga, Charlene F
- Kavalerchik, Edward
- Gotlib, Jason
- Hood, John D
- Durocher, Jeffrey
- Mak, Chi Ching
- Noronha, Glenn
- Soll, Richard M
- Tefferi, Ayalew
- Kaushansky, Ken
- Jamieson, Catriona H M
Producer: 20080425
In:
Cancer cell vol. 13
Availability: No items available.
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10.
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Design, synthesis, structure-function relationship, bioconversion, and pharmacokinetic evaluation of ertapenem prodrugs. [electronic resource] by
- Singh, Sheo B
- Rindgen, Diane
- Bradley, Prudence
- Suzuki, Takao
- Wang, Nengxue
- Wu, Hao
- Zhang, Basheng
- Wang, Li
- Ji, Chongmin
- Yu, Hongshi
- Soll, Richard M
- Olsen, David B
- Meinke, Peter T
- Nicoll-Griffith, Deborah A
Producer: 20150505
In:
Journal of medicinal chemistry vol. 57
Availability: No items available.
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11.
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Development of a New Structural Class of Broadly Acting HCV Non-Nucleoside Inhibitors Leading to the Discovery of MK-8876. [electronic resource] by
- McComas, Casey C
- Palani, Anandan
- Chang, Wei
- Holloway, M Katharine
- Lesburg, Charles A
- Li, Peng
- Liverton, Nigel
- Meinke, Peter T
- Olsen, David B
- Peng, Xuanjia
- Soll, Richard M
- Ummat, Ajay
- Wu, Jie
- Wu, Jin
- Zorn, Nicolas
- Ludmerer, Steven W
Producer: 20170922
In:
ChemMedChem vol. 12
Availability: No items available.
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12.
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A novel series of potent and selective small molecule inhibitors of the complement component C1s. [electronic resource] by
- Subasinghe, Nalin L
- Ali, Farah
- Illig, Carl R
- Jonathan Rudolph, M
- Klein, Scott
- Khalil, Ehab
- Soll, Richard M
- Bone, Roger F
- Spurlino, John C
- DesJarlais, Renee L
- Crysler, Carl S
- Cummings, Maxwell D
- Morris, Philip E
- Kilpatrick, John M
- Sudhakara Babu, Y
Producer: 20050106
In:
Bioorganic & medicinal chemistry letters vol. 14
Availability: No items available.
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13.
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Discovery and SAR of novel Naphthyridines as potent inhibitors of spleen tyrosine kinase (SYK). [electronic resource] by
- Cywin, Charles L
- Zhao, Bao-Ping
- McNeil, Daniel W
- Hrapchak, Matt
- Prokopowicz, Anthony S
- Goldberg, Daniel R
- Morwick, Tina M
- Gao, Amy
- Jakes, Scott
- Kashem, Mohammed
- Magolda, Ronald L
- Soll, Richard M
- Player, Mark R
- Bobko, Mark A
- Rinker, James
- DesJarlais, Renee L
- Winters, Michael P
Producer: 20031205
In:
Bioorganic & medicinal chemistry letters vol. 13
Availability: No items available.
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14.
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Discovery of MK-8742: an HCV NS5A inhibitor with broad genotype activity. [electronic resource] by
- Coburn, Craig A
- Meinke, Peter T
- Chang, Wei
- Fandozzi, Christine M
- Graham, Donald J
- Hu, Bin
- Huang, Qian
- Kargman, Stacia
- Kozlowski, Joseph
- Liu, Rong
- McCauley, John A
- Nomeir, Amin A
- Soll, Richard M
- Vacca, Joseph P
- Wang, Dahai
- Wu, Hao
- Zhong, Bin
- Olsen, David B
- Ludmerer, Steven W
Producer: 20140708
In:
ChemMedChem vol. 8
Availability: No items available.
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15.
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Design and synthesis of 4,5-disubstituted-thiophene-2-amidines as potent urokinase inhibitors. [electronic resource] by
- Rudolph, M Jonathan
- Illig, Carl R
- Subasinghe, Nalin L
- Wilson, Kenneth J
- Hoffman, James B
- Randle, Troy
- Green, David
- Molloy, Chris J
- Soll, Richard M
- Lewandowski, Frank
- Zhang, Marie
- Bone, Roger
- Spurlino, John C
- Deckman, Ingrid C
- Manthey, Carl
- Sharp, Celia
- Maguire, Diane
- Grasberger, Bruce L
- DesJarlais, Renée L
- Zhou, Zhao
Producer: 20020618
In:
Bioorganic & medicinal chemistry letters vol. 12
Availability: No items available.
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16.
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Efficacy of TG101348, a selective JAK2 inhibitor, in treatment of a murine model of JAK2V617F-induced polycythemia vera. [electronic resource] by
- Wernig, Gerlinde
- Kharas, Michael G
- Okabe, Rachel
- Moore, Sandra A
- Leeman, Dena S
- Cullen, Dana E
- Gozo, Maricel
- McDowell, Elizabeth P
- Levine, Ross L
- Doukas, John
- Mak, Chi Ching
- Noronha, Glenn
- Martin, Michael
- Ko, Yon D
- Lee, Benjamin H
- Soll, Richard M
- Tefferi, Ayalew
- Hood, John D
- Gilliland, D Gary
Producer: 20080425
In:
Cancer cell vol. 13
Availability: No items available.
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17.
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Biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s. [electronic resource] by
- Travins, Jeremy M
- Ali, Farah
- Huang, Hui
- Ballentine, Shelley K
- Khalil, Ehab
- Hufnagel, Heather R
- Pan, Wenxi
- Gushue, Joan
- Leonard, Kristi
- Bone, Roger F
- Soll, Richard M
- DesJarlais, Renee L
- Crysler, Carl S
- Ninan, Nisha
- Kirkpatrick, Jennifer
- Cummings, Maxwell D
- Huebert, Norman
- Molloy, Christopher J
- Gaul, Michael
- Tomczuk, Bruce E
- Subasinghe, Nalin L
Producer: 20080519
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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18.
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Design and synthesis of polyethylene glycol-modified biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s. [electronic resource] by
- Subasinghe, Nalin L
- Khalil, Ehab
- Travins, Jeremy M
- Ali, Farah
- Ballentine, Shelley K
- Hufnagel, Heather R
- Pan, Wenxi
- Leonard, Kristi
- Bone, Roger F
- Soll, Richard M
- Crysler, Carl S
- Ninan, Nisha
- Kirkpatrick, Jennifer
- Kolpak, Michael X
- Diloreto, Karen A
- Eisennagel, Stephen H
- Huebert, Norman D
- Molloy, Christopher J
- Tomczuk, Bruce E
- Gaul, Michael D
Producer: 20121130
In:
Bioorganic & medicinal chemistry letters vol. 22
Availability: No items available.
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19.
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Alternative core development around the tetracyclic indole class of HCV NS5A inhibitors. [electronic resource] by
- Tong, Ling
- Yu, Wensheng
- Coburn, Craig A
- Meinke, Peter T
- Nair, Anilkumar G
- Dwyer, Michael P
- Chen, Lei
- Selyutin, Oleg
- Rosenblum, Stuart B
- Jiang, Yueheng
- Fells, James
- Hu, Bin
- Zhong, Bin
- Soll, Richard M
- Liu, Rong
- Agrawal, Sony
- Xia, Ellen
- Zhai, Ying
- Kong, Rong
- Ingravallo, Paul
- Nomeir, Amin
- Asante-Appiah, Ernest
- Kozlowski, Joseph A
Producer: 20170808
In:
Bioorganic & medicinal chemistry letters vol. 26
Availability: No items available.
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