The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response. [electronic resource]
Producer: 20130321Description: 106-18 p. digitalISSN:- 1097-4180
- Animals
- Antiviral Agents -- pharmacology
- Binding Sites
- Bone Marrow Cells -- drug effects
- Gene Expression Regulation
- Hydroxycholesterols -- metabolism
- Interferons -- pharmacology
- Liver X Receptors
- Macrophage Activation -- drug effects
- Macrophages -- drug effects
- Mevalonic Acid -- metabolism
- Mice
- Orphan Nuclear Receptors -- metabolism
- Promoter Regions, Genetic
- Protein Binding
- STAT1 Transcription Factor -- metabolism
- Steroid Hydroxylases -- genetics
- Virus Replication -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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