Proteasomal degradation of the histone acetyl transferase p300 contributes to beta-cell injury in a diabetes environment. [electronic resource]
Producer: 20191105Description: 600 p. digitalISSN:- 2041-4889
- Acetylation
- Animals
- Apoptosis -- drug effects
- Cytokines -- metabolism
- Diabetes Mellitus -- enzymology
- E1A-Associated p300 Protein -- genetics
- Glucose -- toxicity
- Histones -- metabolism
- Humans
- Inflammation Mediators -- metabolism
- Insulin-Secreting Cells -- drug effects
- Male
- Melatonin -- metabolism
- Mice, Inbred C57BL
- Proteasome Endopeptidase Complex -- metabolism
- Proteolysis -- drug effects
- RNA, Messenger -- genetics
- Receptors, Melatonin -- metabolism
- Signal Transduction
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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