The metabolic modulators, Etomoxir and NVP-LAB121, fail to reverse pressure overload induced heart failure in vivo. [electronic resource]
Producer: 20091204Description: 547-57 p. digitalISSN:- 1435-1803
- Animals
- Cardiomegaly -- drug therapy
- Carnitine O-Palmitoyltransferase -- antagonists & inhibitors
- Disease Models, Animal
- Energy Metabolism -- drug effects
- Enzyme Inhibitors -- pharmacology
- Epoxy Compounds -- pharmacology
- Fatty Acids -- metabolism
- Glucose -- metabolism
- Heart Failure -- drug therapy
- Hypertension -- complications
- Male
- Myocardial Contraction -- drug effects
- Myocardium -- enzymology
- Myosin Heavy Chains -- metabolism
- Oxidation-Reduction
- Piperazines -- pharmacology
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Pyruvate Dehydrogenase Acetyl-Transferring Kinase
- Rats
- Rats, Sprague-Dawley
- Stroke Volume -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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