Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro. [electronic resource]
Producer: 20070305Description: 912-25 p. digitalISSN:- 0270-7306
- Animals
- Carcinoma, Renal Cell -- pathology
- Cell Hypoxia -- drug effects
- Electron Transport -- drug effects
- Electrophoresis, Polyacrylamide Gel
- Energy Metabolism -- drug effects
- Gene Expression Regulation -- drug effects
- Humans
- Hydrogen Peroxide -- pharmacology
- Hydroxylation -- drug effects
- Hypoxia-Inducible Factor 1, alpha Subunit -- genetics
- Mice
- Mitochondria -- drug effects
- Molecular Mimicry -- drug effects
- Oxidation-Reduction -- drug effects
- Procollagen-Proline Dioxygenase -- metabolism
- Proline -- chemistry
- Protein Transport -- drug effects
- RNA, Messenger -- genetics
- Recombinant Fusion Proteins -- metabolism
- Thermodynamics
- Uncoupling Agents -- pharmacology
- Von Hippel-Lindau Tumor Suppressor Protein -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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