The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration. [electronic resource]
Producer: 20170613Description: 576-584 p. digitalISSN:- 1468-2060
- ARNTL Transcription Factors -- analysis
- Age Factors
- Aging -- physiology
- Animals
- CLOCK Proteins -- analysis
- Cells, Cultured
- Circadian Clocks -- drug effects
- Circadian Rhythm -- drug effects
- Humans
- Interleukin-1beta -- pharmacology
- Intervertebral Disc -- chemistry
- Intervertebral Disc Degeneration -- genetics
- Mice
- Mice, Knockout
- NF-kappa B -- antagonists & inhibitors
- Nucleus Pulposus -- chemistry
- Period Circadian Proteins -- genetics
- Signal Transduction
- Temperature
- Tissue Culture Techniques
- Transcriptome
- Transfection
- Tumor Necrosis Factor-alpha -- pharmacology
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Publication Type: Journal Article
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