Drosophila deoxyribonucleoside kinase mutants with enhanced ability to phosphorylate purine analogs. [electronic resource]
Producer: 20071108Description: 1278-86 p. digitalISSN:- 0969-7128
- Animals
- Antimetabolites
- Antineoplastic Agents -- therapeutic use
- Cell Line, Tumor
- Cladribine -- therapeutic use
- Cytarabine -- therapeutic use
- Directed Molecular Evolution -- methods
- Drosophila melanogaster -- enzymology
- Genes, Transgenic, Suicide
- Genetic Therapy -- methods
- Glioblastoma -- therapy
- Humans
- Lethal Dose 50
- Mutation
- Neoplasms -- therapy
- Osteosarcoma -- therapy
- Phosphorylation
- Phosphotransferases (Alcohol Group Acceptor) -- genetics
- Purines -- metabolism
- Substrate Specificity
- Transduction, Genetic -- methods
- Vidarabine -- analogs & derivatives
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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