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Design and Elaboration of a Tractable Tricyclic Scaffold To Synthesize Druglike Inhibitors of Dipeptidyl Peptidase-4 (DPP-4), Antagonists of the C-C Chemokine Receptor Type 5 (CCR5), and Highly Potent and Selective Phosphoinositol-3 Kinase δ (PI3Kδ) Inhibitors. [electronic resource] by
- Schwehm, Carolin
- Kellam, Barrie
- Garces, Aimie E
- Hill, Stephen J
- Kindon, Nicholas D
- Bradshaw, Tracey D
- Li, Jin
- Macdonald, Simon J F
- Rowedder, James E
- Stoddart, Leigh A
- Stocks, Michael J
Producer: 20170616
In:
Journal of medicinal chemistry vol. 60
Availability: No items available.
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5.
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The Design of Potent, Selective and Drug-Like RGD αvβ1 Small-Molecule Inhibitors Derived from non-RGD α4β1 Antagonists. [electronic resource] by
- Hatley, Richard J D
- Barrett, Tim N
- Slack, Robert J
- Watson, Morag E
- Baillache, Daniel J
- Gruszka, Anna
- Washio, Yoshiaki
- Rowedder, James E
- Pogány, Peter
- Pal, Sandeep
- Macdonald, Simon J F
Producer: 20200706
In:
ChemMedChem vol. 14
Availability: No items available.
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The discovery of quinoline based single-ligand human H [electronic resource] by
- Procopiou, Panayiotis A
- Ancliff, Rachael A
- Gore, Paul M
- Hancock, Ashley P
- Hodgson, Simon T
- Holmes, Duncan S
- Keeling, Steven P
- Looker, Brian E
- Parr, Nigel A
- Rowedder, James E
- Slack, Robert J
Producer: 20170627
In:
Bioorganic & medicinal chemistry letters vol. 26
Availability: No items available.
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Design of Phthalazinone Amide Histamine H [electronic resource] by
- Procopiou, Panayiotis A
- Ford, Alison J
- Gore, Paul M
- Looker, Brian E
- Hodgson, Simon T
- Holmes, Duncan S
- Vile, Sadie
- Clark, Kenneth L
- Saunders, Ken A
- Slack, Robert J
- Rowedder, James E
- Watts, Clarissa J
Publication details: ACS medicinal chemistry letters May 2017
In:
ACS medicinal chemistry letters vol. 8
Availability: No items available.
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Discovery of an Orally Bioavailable Pan αv Integrin Inhibitor for Idiopathic Pulmonary Fibrosis. [electronic resource] by
- Anderson, Niall A
- Campos, Sebastien
- Butler, Sharon
- Copley, Royston C B
- Duncan, Ian
- Harrison, Stephen
- Le, Joelle
- Maghames, Rosemary
- Pastor-Garcia, Aleix
- Pritchard, John M
- Rowedder, James E
- Smith, Claire E
- Thomas, Jack
- Vitulli, Giovanni
- Macdonald, Simon J F
Producer: 20200615
In:
Journal of medicinal chemistry vol. 62
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Pyrazolopyridazine alpha-2-delta-1 ligands for the treatment of neuropathic pain. [electronic resource] by
- Myatt, James W
- Healy, Mark P
- Bravi, Gianpaolo S
- Billinton, Andrew
- Johnson, Christopher N
- Matthews, Kim L
- Jandu, Karamjit S
- Meng, Wenjing
- Hersey, Anne
- Livermore, David G
- Douault, Clement B
- Witherington, Jason
- Bit, Rino A
- Rowedder, James E
- Brown, Jason D
- Clayton, Nick M
Producer: 20101123
In:
Bioorganic & medicinal chemistry letters vol. 20
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10.
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Profile of a Highly Selective Quaternized Pyrrolidine Betaine α [electronic resource] by
- Barrett, Tim N
- Taylor, Jonathan A
- Barker, Daniel
- Procopiou, Panayiotis A
- Thompson, James D F
- Barrett, John
- Le, Joelle
- Lynn, Sean M
- Pogany, Peter
- Pratley, Cassie
- Pritchard, John M
- Roper, James A
- Rowedder, James E
- Slack, Robert J
- Vitulli, Giovanni
- Macdonald, Simon J F
- Kerr, William J
Producer: 20200622
In:
Journal of medicinal chemistry vol. 62
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11.
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Structure Activity Relationships of αv Integrin Antagonists for Pulmonary Fibrosis by Variation in Aryl Substituents. [electronic resource] by
- Adams, James
- Anderson, Edward C
- Blackham, Emma E
- Chiu, Yin Wa Ryan
- Clarke, Thomas
- Eccles, Natasha
- Gill, Luke A
- Haye, Joshua J
- Haywood, Harvey T
- Hoenig, Christian R
- Kausas, Marius
- Le, Joelle
- Russell, Hannah L
- Smedley, Christopher
- Tipping, William J
- Tongue, Tom
- Wood, Charlotte C
- Yeung, Jason
- Rowedder, James E
- Fray, M Jonathan
- McInally, Thomas
- Macdonald, Simon J F
Producer: 20141121
In:
ACS medicinal chemistry letters vol. 5
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12.
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Discovery of ( S)-3-(3-(3,5-Dimethyl-1 H-pyrazol-1-yl)phenyl)-4-(( R)-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic Acid, a Nonpeptidic α [electronic resource] by
- Procopiou, Panayiotis A
- Anderson, Niall A
- Barrett, John
- Barrett, Tim N
- Crawford, Matthew H J
- Fallon, Brendan J
- Hancock, Ashley P
- Le, Joelle
- Lemma, Seble
- Marshall, Richard P
- Morrell, Josie
- Pritchard, John M
- Rowedder, James E
- Saklatvala, Paula
- Slack, Robert J
- Sollis, Steven L
- Suckling, Colin J
- Thorp, Lee R
- Vitulli, Giovanni
- Macdonald, Simon J F
Producer: 20191014
In:
Journal of medicinal chemistry vol. 61
Availability: No items available.
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