ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo. [electronic resource]
Producer: 20100430Description: 623-35 p. digitalISSN:- 1540-9538
- ADAM Proteins -- deficiency
- ADAM10 Protein
- Amyloid Precursor Protein Secretases -- deficiency
- Animals
- B-Lymphocytes -- immunology
- DNA, Complementary -- genetics
- Exons -- genetics
- Gene Amplification
- Gene Deletion
- Macrophages -- physiology
- Membrane Proteins -- deficiency
- Mice
- Mice, Knockout
- Polymerase Chain Reaction
- RNA -- genetics
- Receptor, Notch2 -- genetics
- Receptors, CCR1 -- genetics
- Receptors, IgE -- metabolism
- Recombination, Genetic
- Reverse Transcriptase Polymerase Chain Reaction
- Spleen -- physiology
- T-Lymphocytes -- immunology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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