Pharmacological characterization in vitro of EP2306 and EP2302, potent inhibitors of squalene synthase and lipid biosynthesis. [electronic resource]
Producer: 20060621Description: 34-42 p. digitalISSN:- 0014-2999
- Animals
- Apolipoproteins B -- metabolism
- Biological Transport -- drug effects
- Biphenyl Compounds -- pharmacology
- Cell Line, Tumor
- Cholesterol -- biosynthesis
- Dose-Response Relationship, Drug
- Enzyme Inhibitors -- pharmacology
- Farnesyl-Diphosphate Farnesyltransferase -- antagonists & inhibitors
- Humans
- Lipids -- biosynthesis
- Lipoproteins, LDL -- pharmacokinetics
- Microscopy, Fluorescence
- Microsomes, Liver -- drug effects
- Morpholines -- pharmacology
- Rabbits
- Receptors, LDL -- metabolism
- Simvastatin -- pharmacology
- Triglycerides -- biosynthesis
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Publication Type: Journal Article
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