The antiaggregating activity of clopidogrel is due to a metabolic activation by the hepatic cytochrome P450-1A. [electronic resource]
Producer: 19950221Description: 313-7 p. digitalISSN:- 0340-6245
- Adenosine Diphosphate -- antagonists & inhibitors
- Animals
- Biotransformation
- Chromatography, High Pressure Liquid
- Clopidogrel
- Cytochrome P-450 Enzyme System -- classification
- Female
- Isoenzymes -- metabolism
- Microsomes, Liver -- enzymology
- Platelet Aggregation -- drug effects
- Platelet Aggregation Inhibitors -- pharmacokinetics
- Rats
- Rats, Sprague-Dawley
- Ticlopidine -- analogs & derivatives
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Publication Type: Journal Article
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