PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells. [electronic resource]
Producer: 20130225Description: 2441-53 p. digitalISSN:- 1540-9538
- 3-Phosphoinositide-Dependent Protein Kinases
- Animals
- Aryl Hydrocarbon Receptor Nuclear Translocator -- genetics
- CD8-Positive T-Lymphocytes -- cytology
- Cell Differentiation -- physiology
- Cell Movement -- physiology
- Chemokines -- metabolism
- Gene Expression Regulation
- Glucose -- metabolism
- Glycolysis
- Hypoxia-Inducible Factor 1 -- genetics
- Hypoxia-Inducible Factor 1, alpha Subunit -- genetics
- Interleukin-2 -- pharmacology
- Mechanistic Target of Rapamycin Complex 1
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Mice, Transgenic
- Multiprotein Complexes
- Phosphatidylinositol 3-Kinases -- genetics
- Protein Serine-Threonine Kinases -- genetics
- Proteins -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Receptors, Antigen, T-Cell -- metabolism
- Receptors, Chemokine -- metabolism
- TOR Serine-Threonine Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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