Results
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1.
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Design and synthesis of novel CCR2 antagonists: investigation of non-aryl/heteroaryl binding motifs. [electronic resource] by
- Trujillo, John I
- Huang, Wei
- Hughes, Robert O
- Rogier, D Joseph
- Turner, Steven R
- Devraj, Rajesh
- Morton, Philip A
- Xue, Chu-Biao
- Chao, Ganfeng
- Covington, Maryanne B
- Newton, Robert C
- Metcalf, Brian
Producer: 20110705
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
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2.
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Discovery of INCB10820/PF-4178903, a potent, selective, and orally bioavailable dual CCR2 and CCR5 antagonist. [electronic resource] by
- Zheng, Changsheng
- Cao, Ganfeng
- Xia, Michael
- Feng, Hao
- Glenn, Joseph
- Anand, Rajan
- Zhang, Ke
- Huang, Taisheng
- Wang, Anlai
- Kong, Ling
- Li, Mei
- Galya, Laurine
- Hughes, Robert O
- Devraj, Rajesh
- Morton, Phillip A
- Rogier, D Joseph
- Covington, Maryanne
- Baribaud, Fred
- Shin, Niu
- Scherle, Peggy
- Diamond, Sharon
- Yeleswaram, Swamy
- Vaddi, Kris
- Newton, Robert
- Hollis, Greg
- Friedman, Steven
- Metcalf, Brian
- Xue, Chu-Biao
Producer: 20110614
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
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3.
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Optimization of the aminopyridopyrazinones class of PDE5 inhibitors: discovery of 3-[(trans-4-hydroxycyclohexyl)amino]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one. [electronic resource] by
- Hughes, Robert O
- Walker, John K
- Rogier, D Joseph
- Heasley, Steve E
- Blevis-Bal, Rhadika M
- Benson, Alan G
- Jacobsen, E Jon
- Cubbage, Jerry W
- Fobian, Yvette M
- Owen, Dafydd R
- Freskos, John N
- Molyneaux, John M
- Brown, David L
- Acker, Brad A
- Maddux, Todd M
- Tollefson, Mike B
- Moon, Joseph B
- Mischke, Brent V
- Rumsey, Jeanne M
- Zheng, Yi
- MacInnes, Alan
- Bond, Brian R
- Yu, Ying
Producer: 20091124
In:
Bioorganic & medicinal chemistry letters vol. 19
Availability: No items available.
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4.
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Discovery of INCB8761/PF-4136309, a Potent, Selective, and Orally Bioavailable CCR2 Antagonist. [electronic resource] by
- Xue, Chu-Biao
- Wang, Anlai
- Han, Qi
- Zhang, Yingxin
- Cao, Ganfeng
- Feng, Hao
- Huang, Taisheng
- Zheng, Changsheng
- Xia, Michael
- Zhang, Ke
- Kong, Lingquan
- Glenn, Joseph
- Anand, Rajan
- Meloni, David
- Robinson, D J
- Shao, Lixin
- Storace, Lou
- Li, Mei
- Hughes, Robert O
- Devraj, Rajesh
- Morton, Philip A
- Rogier, D Joseph
- Covington, Maryanne
- Scherle, Peggy
- Diamond, Sharon
- Emm, Tom
- Yeleswaram, Swamy
- Contel, Nancy
- Vaddi, Kris
- Newton, Robert
- Hollis, Greg
- Metcalf, Brian
Producer: 20140605
In:
ACS medicinal chemistry letters vol. 2
Availability: No items available.
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5.
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Investigation of aminopyridiopyrazinones as PDE5 inhibitors: Evaluation of modifications to the central ring system. [electronic resource] by
- Hughes, Robert O
- Walker, John K
- Cubbage, Jerry W
- Fobian, Yvette M
- Rogier, D Joseph
- Heasley, Steve E
- Blevis-Bal, Rhadika M
- Benson, Alan G
- Owen, Dafydd R
- Jacobsen, E Jon
- Freskos, John N
- Molyneaux, John M
- Brown, David L
- Stallings, William C
- Acker, Brad A
- Maddux, Todd M
- Tollefson, Mike B
- Williams, Jennifer M
- Moon, Joseph B
- Mischke, Brent V
- Rumsey, Jeanne M
- Zheng, Yi
- Macinnes, Alan
- Bond, Brian R
- Yu, Ying
Producer: 20091207
In:
Bioorganic & medicinal chemistry letters vol. 19
Availability: No items available.
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6.
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Design, synthesis, and biological evaluation of 3-[4-(2-hydroxyethyl)piperazin-1-yl]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one, a potent, orally active, brain penetrant inhibitor of phosphodiesterase 5 (PDE5). [electronic resource] by
- Hughes, Robert O
- Rogier, D Joseph
- Jacobsen, E Jon
- Walker, John K
- Macinnes, Alan
- Bond, Brian R
- Zhang, Lena L
- Yu, Ying
- Zheng, Yi
- Rumsey, Jeanne M
- Walgren, Jennie L
- Curtiss, Sandra W
- Fobian, Yvette M
- Heasley, Steven E
- Cubbage, Jerry W
- Moon, Joseph B
- Brown, David L
- Acker, Brad A
- Maddux, Todd M
- Tollefson, Mike B
- Mischke, Brent V
- Owen, Dafydd R
- Freskos, John N
- Molyneaux, John M
- Benson, Alan G
- Blevis-Bal, Rhadika M
Producer: 20100504
In:
Journal of medicinal chemistry vol. 53
Availability: No items available.
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