Tacrolimus-Induced BMP/SMAD Signaling Associates With Metabolic Stress-Activated FOXO1 to Trigger β-Cell Failure. [electronic resource]
Producer: 20200702Description: 193-204 p. digitalISSN:- 1939-327X
- Animals
- Bone Morphogenetic Proteins -- genetics
- Cell Transdifferentiation
- Cells, Cultured
- DNA-Binding Proteins -- genetics
- Forkhead Box Protein O1 -- genetics
- Gene Expression Regulation -- drug effects
- Glucose -- pharmacology
- Humans
- Immunosuppressive Agents -- pharmacology
- Insulin-Secreting Cells -- drug effects
- Male
- Mice
- Mice, Knockout
- Palmitic Acid -- pharmacology
- Signal Transduction -- drug effects
- Smad Proteins -- genetics
- Stress, Physiological -- drug effects
- Tacrolimus -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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