Ubiquitin/26S proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells. [electronic resource]
Producer: 20010816Description: 5926-32 p. digitalISSN:- 0008-5472
- Animals
- Breast Neoplasms -- drug therapy
- CHO Cells
- Camptothecin -- pharmacology
- Cell Line
- Colonic Neoplasms -- drug therapy
- Cricetinae
- DNA Topoisomerases, Type I -- biosynthesis
- Down-Regulation -- drug effects
- Drug Resistance, Neoplasm -- physiology
- Fibroblasts -- drug effects
- Gene Expression Regulation, Enzymologic -- drug effects
- Humans
- KB Cells -- drug effects
- Peptide Hydrolases -- metabolism
- Proteasome Endopeptidase Complex
- Ubiquitins -- metabolism
No physical items for this record
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
There are no comments on this title.
Log in to your account to post a comment.