Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade. [electronic resource]
Producer: 20190627Description: 43-48 p. digitalISSN:- 1476-4687
- Adenosine Deaminase -- deficiency
- Animals
- CRISPR-Cas Systems -- genetics
- Cell Cycle Checkpoints -- drug effects
- Cell Line, Tumor
- Drug Resistance, Neoplasm -- drug effects
- Female
- Histocompatibility Antigens Class I -- immunology
- Immunotherapy
- Inflammation -- genetics
- Interferon-Induced Helicase, IFIH1 -- metabolism
- Interferons -- immunology
- Melanoma, Experimental -- drug therapy
- Mice
- Mice, Inbred C57BL
- Phenotype
- Programmed Cell Death 1 Receptor -- antagonists & inhibitors
- RNA Editing
- RNA, Double-Stranded -- genetics
- RNA-Binding Proteins -- genetics
- Receptors, G-Protein-Coupled -- metabolism
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Publication Type: Journal Article
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